Raynauds Disease1

Question 1

What labs should be tested on patients with Raynauds

Answer 1

antinuclear antibody (ANA), rheumatoid factor (RF), double stranded DNA, single stranded DNA

Question 2

What additional sx�s should be asked about in a patient presenting with Raynauds

Answer 2

sclerodactyly, dysphagia, arthralgia, xerostomia

Question 3

What is the classic triad found in Raynauds syndrome

Answer 3

pallor from artery spasm, cyanosis from slow perfusion, reactive hyperemia

Question 4

What is the medical tx of choice for Raynauds

Answer 4

calcium channel blockers: nifedipine or diltiazem

Question 5

What are other medications (other than CCB) that can be used for Raynauds

Answer 5

ACE, ARB, sildenafil

Question 6

What is the mechanism of Sildenafil

Answer 6

PDE-I -greater than increases cGMP levels in vascular smooth muscle to induce vasodilation

Question 7

When is surgery indicated with Raynauds

Answer 7

ulcers, severe ischemia and necrosis

Question 8

What surgical interventions are performed in Raynauds

Answer 8

debridements of ulcers, sympathectomy, and amputation when necessary

Question 9

What type of sympathectomy is usually used in Raynauds

Answer 9

cervico-thoracic

Question 10

What is the adverse effect of a cervico-thoracic sympathectomy for Raynauds

Answer 10

Horners syndrome