Infected Grafts Flashcards

1
Q

MC organism responsible for infected grafts

A

Staph aureus

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2
Q

What other organisms are common in infected grafts

A

MRSA, E coli, Enterobacter, Klebsiella, Proteus, Psuedomonas

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3
Q

Late infections are commonly caused by which organisms

A

S. epidermidis

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4
Q

What organism produces a polysaccharide biofilm

A

S. epidermidis

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5
Q

How can local infection present

A

sinus tract, perigraft fluid collection, anastomotic pseudoaneurysm, aortoenteric fistula

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6
Q

Define late graft infection

A

greater than 4 months after graft implantation

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7
Q

If a patient presents with GI hemorrhage and known intraabdominal graft what diagnosis should be assumed

A

aortoenteric fistula

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8
Q

Where can an aortoenteric fistula be located

A

anywhere within the bowel, MC 3rd and 4th portion of the duodenum

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9
Q

Diagnostic imaging of aortoenteric fistula

A

Duplex US, CT, MRI

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10
Q

What test should be promptly performed in a patient with UGI hemorrhage and a graft

A

upper endoscopy

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11
Q

When complete excision of a graft is required what are the surgical options

A
  1. ax-bifem, 2. bilateral ax-profunda, 3. bilateral ax-popliteal 4. bilateral ax-superficial femoral bypass
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12
Q

If UGI is negative for aortoenteric fistula should further workup be done

A

yes

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13
Q

Is the risk of limb loss greater with an infrainguinal prosthetic graft

A

yes

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14
Q

When can graft salvage be considered

A

if no systemic sepsis, thrombosis, septic emboli or Psuedomonas

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15
Q

What is the approach to graft salvage

A

local debridement, IV abx and local abx, muscle flaps for coverage

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16
Q

What is the reinfection rate in graft salvage

A

35%

17
Q

What are options for muscle flaps of the groin

A

rectus abdominis, rectus femoris, tensor fascia lata, gracilis

18
Q

What are options for muscle flaps of the knee

A

gastrocnemius and soleus

19
Q

What are graft options for the chest

A

pec major, latissimus dorsi

20
Q

What are graft options for head and neck

A

SCM

21
Q

Why are muscle flaps used

A

well vascularized tissue raise local oxygen tension and fascilitate delivery of abx to the infected region