Claudication1 Flashcards
1
Q
Name the 3 presentations of peripheral arterial disease
A
- subclinical 2. intermittent claudication 3. critical limb ischemia
2
Q
Medical tx of claudication
A
modify cardiovascular risk factors: HTN, DM, HLD, smoking, walking
3
Q
What 2 drugs help with tx of claudication
A
Pentoxyfylline and Cilostazol
4
Q
What is the mechanism of Pentoxyfylline
A
improves oxygen delivery through its effect on RBC�s wall flexibility and decreases blood viscosity
5
Q
What is the mechanism of Cilostazol
A
PDE-3 inhibitor- increases cAMP, enhancing muscle performance
6
Q
What are side effects of Cilostazol
A
headache, diarrhea, GI problems
7
Q
Who is Cilostazol contraindicated in
A
CHF patients
