Rate Limiting Enzymes Flashcards
1
Q
Glycolysis
A
PFK-1 (phosphofructokinase 1)
2
Q
Gluconeogenesis
A
Fructose-1,6,-bisphosphatase
3
Q
TCA cycle
A
Isocitrate Dehydrogenase
4
Q
Glycogenesis
A
Glycogen Synthase
5
Q
Glycogenolysis
A
Glycogen Phosphorylase
6
Q
HMP Shunt
A
G6PD (Glucose-6-phosphate dehydrogenase)
7
Q
De Novo Pyrimidine Synthesis
A
CPS- II (carbamoyl phosphate synthetase)
8
Q
De Novo Purine Synthesis
A
Glutamine-PRPP Amidotransferase
9
Q
Urea Cycle
A
CPS-1
10
Q
Fatty Acid Synthesis
-where?
A
Acetyl CoA Carboxylase (ACC)
Cytoplasm
11
Q
Fatty Acid Oxidation (breakdown) aka beta-oxidation
-where?
A
Carnitine Acyltransferase I
Mitochondria
12
Q
Ketogenesis
-where?
A
HMG-CoA Synthase
Mitochondria
13
Q
Cholesterol Synthesis
-where?
A
HMG-CoA Reductase
Cytoplasm
