Rat quiz Flashcards

(53 cards)

1
Q

Majority of lab rats are what species?

A

Brown rat or Norway Rat

aka: Rattus norvegicus

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2
Q

How many chromasomes does the brown rat have?

A

42

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3
Q

All rodents have a single pair of _____ on each jaw

A

Incisors

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4
Q

___% of the rat consists of its’ tail

A

85%

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5
Q

What are two uses of a rat’s tail?

A

Balance and heat abatement

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6
Q

Where are a rat’s sweatglands found?

A

Hairless foot pads

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7
Q

How many digits are on the front and hind limbs?

A

4 on front, 5 on back

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8
Q

What is the anatomical feature responsible for red eyes in the rat?

A

Harderian gland (lacrimal gland containing prophyrin)

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9
Q

What is chromodacryorrhea?

A

Increase in red tears caused by stress or disease

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10
Q

What is the average life span for a rat?

A

26-40 months

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11
Q

What is the average weight for a male rat?

A

267-500g

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12
Q

What is the average weight for a female rat?

A

225-325g

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13
Q

What is the normal HR for a rat?

A

313-493 bpm

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14
Q

What is the normal RR for a rate?

A

71-146 bpm

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15
Q

What is the normal temperature for a rat?

A

96.6-99.5

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16
Q

What is the daily feed consumption for a rat?

A

15-20 g

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17
Q

What is the daily water consumption for a rat?

A

22-33ml

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18
Q

What is the recommended evironmental temp for rats?

A

21-24 degrees C

Humidity 45-55%

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19
Q

What is the gestation length for rats?

A

21-23 days

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20
Q

What type of estrus cycle do rats have?

A

Continuous polyestrus

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21
Q

Why are rats useful for toxicology studies?

A

Inability to vomit

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22
Q

Type of rat that has been randomly bred; not inbred. Referred to as outbred.

23
Q

Type of rat that has been inbred

24
Q

What is the goal of a strain?

A

Develop a strain of animals that are genetically homozygous

25
What is inbreeding depression?
Decrease in reproductive capability of successive generations
26
A strain is designated with what?
Upper case letters
27
A substrain will have a ___ \_\_\_\_ after the strain designation
Slanted Line
28
Develop as a result of genetic mutation in existing strains, then perpetuated in future generations
Coisogenic
29
In what manner are Athymic (nude) animals developed?
Congenic
30
What is an F1 hybrid?
Direct result of mating between 2 different inbred strains
31
—Derived by removing specific DNA sequences from one strain or species & inserting them into an ovum just after fertilization. The ovum is then transplanted into a pseudopregnant female that serves as a serrogate. Used for gene-related disorders.
Transgenic Animals
32
—Removes or blocks a specific gene from an animal; used to study diseases associated with defective genes. Ex) Sickle cell anemia; cystic fibrosis.
Knockout animals
33
What animals assist in the development of gene therapy?
Knockout animals
34
Albany rats are linked to what disease?
Mammary tumors
35
Brown rats are linked to what disease?
Myeloid leukemia
36
Buffalo rats are linked to what disease?
Autoimmune
37
Fisher 344 rats are linked to what disease?
Esophogeal and bladder cancer
38
What are some common strategies used to confirm genetic purity?
Protein electrophoresis, serologic testing, mandible measurement and backcross mating
39
What is the preferred bedding for rat housing?
hardwood shavings or corn cob
40
Why are soft woods not used for bedding?
Respiratory problems and hepatic issues
41
What can excess noise cause?
Audiogenic seizures, cannabolism and decreased reproductive rates
42
What can low humidity cause?
Ring tail
43
Pregnant/lactating females require \_\_X the amount of normal nutrition
4X
44
Rat food should contain \_\_-\_\_% protein and \_\_% fat
20-25% protein and 4% fat
45
What is the shelf life for most commercial foods?
6 months passed milling date
46
What are three different restraint tools for rats?
Plastic restraint boxes, stockinette, plastic cone
47
Bacterial disease caused by Bacillus piliformis causing hepatic necrosis and myocardial degeneration
Tyzzer's disease
48
Opportunistic pathogen, causes URI and pneumonia
Pasteurellosis
49
Rare bacterial disease in rats characterized by chromodacryorrhea, nasopharynx inflammation, pleuritis and meningitis
Streptococcus
50
"Rat bite fever" or "Haverhill fever" Present in nasopharynx of normal rats, not disease causing agent
Streptobacillosis
51
Most significant viral diseas of rats
Sialodacryoadenitis
52
Viral disease that usually remains subclinical in rats
Sendai virus
53