Mice Flashcards

1
Q

What family of mice is considered “house mice”?

A

Muridae family or Swiss albino mouse

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2
Q

Unlike other mammals, what remains active throughout their life?

A

Marrow of long bone

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3
Q

What is barbering?

A

Chewing off of hair of cagemates

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4
Q

What in males is 50% larger than females?

A

Spleen

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5
Q

What is the average life span of a mouse?

A

12-36 months

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6
Q

What is the recommended humidity?

A

45-55%

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7
Q

What is the recommended environmental temp?

A

24-25 C

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8
Q

Mice have __ pairs of mammary glands that extend to sides and back

A

5 pairs

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9
Q

What type of estrus do mice have?

A

Continuously polyestrus

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10
Q

What should be done to females to decrease likelihood of cannibalism?

A

Leave females undistrubed for 2 days after parturition

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11
Q

At what age do females mice develop nipples?

A

9 days

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12
Q

At what age do mice pup ears open?

A

Day 3

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13
Q

At what age do mice pups eyes open?

A

Day 12-14

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14
Q

What is the most common breeding system?

A

Polygamous (1 male with several females)

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15
Q

Until what age are females bred?

A

9 months

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16
Q

What is the term for when large groups of female mice aer housed together without the presence of a male, allowing females to go into anestrus and allows for timed mating

A

Whitten Effect

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17
Q

What is the term for if a pregnant mous is exposed to a new male or its odor within 4 days of breeding. The existing pregnancy will be aborted and the female will return to estrus

A

Bruce Effect

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18
Q

What are some commonly used outbred stocks of mice?

A

Swiss, swiss Webster, CD 1, CFI SKH1

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19
Q

What outbred stock is the hairless breed?

A

SKH1

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20
Q

Most cases of pneumonia are caused by what bacteria?

A

Mycoplasma pulmonis

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21
Q

What bacteria is responsible for Tyzzers disease?

A

Bacillus piliformis

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22
Q

Why is Tyzzers difficult to eradicate?

A

Resistant spores

23
Q

Bacterial disease that may be fatal in athymic mice or immunocompromised mice

A

Pasteurellosis

24
Q

Heliobacter bacteria that can cause IBD and hepatic tumors

A

Hepatitis

25
Q

Treatment for hepatitis includes amoxicillen, metronidazole, and bismuth PO SID X 2 weeks and should never be given via what method?

A

Never put in water

26
Q

What two bacterial diseases are zoonotic?

A

Lepto and streptobacillus moniliformis

27
Q

What is the primary agent of viral respiratory disease?

A

Sendai virus

28
Q

Viral disease uncommon in the US, mouse is the only known host, highly contagious, can be acute, chronic or latent

A

Mousepox or ectromelia

29
Q

Zoonotic viral disease spread via aersols, bite wounds, transplacental, arthropod vectors. Infected in utero.

A

Lymphocytic choriomeningitis

30
Q

Corona virus of mice. Enteric strains are most common, altho respiratory strains exist. Treatment not usually attempted

A

Mouse hepatitis virus

31
Q

Clinical disease only seen in suckling mice, dread fecal oral route, transplacental. Potentially zoonotic. No treatment

A

Reovirus type 3

32
Q

Acquired through close contact with birds or their feces

A

Histoplasma capsulatum

33
Q

Rickettsial blood parasite

A

Eperythrozoon coccoides

34
Q

Most common neoplasia in random bred mice

A

Pulmonary tumors

35
Q

Trauma in mice housed together, lesions often become infected with what?

A

S. aureus

36
Q

What are best used to monitor mice under anesthesia?

A

NM system and RR

37
Q

What makes mice useful for teratology, genetics and gerontology?

A

High fecundity, short gestation, short life span

38
Q

Susceptibilty to specific viruses and development of certain tumors makes mice useful in what studies?

A

Virology and oncology

39
Q

Bacterial disease characterized by thickening of intestinal mucosa, mice are most affected species, symptoms include exposive diarrhea and prolapsed rectum.

A

Transmissible murine colonic hyperplasia

~citrobacter freundii

40
Q

What two bacterial diseases are dermatitis?

A

S. aureus and Streptococcus species

41
Q

How is Sendai virus spread?

A

Direct contact or aerosol contamination

42
Q

Treatment for mousepox (ectromelia)?

A

None

43
Q

What serves as the source of infection for mousepox?

A

Older animals that harbor infection in GI tract

44
Q

Chronic rash and swelling/necrosis of limbs is indicative of what disease?

A

Mousepox

45
Q

What is the main source of Mousepox (ectromelia)?

A

Mice/biologics imported

46
Q

How is mouse hepatitis virus transmitted?

A

Direct contact, oral-nasal, fomites, transplacental

47
Q

True or False

Systemic infections in mice are rare

A

True

48
Q

What is the intermediate host for Moniliformis moniliformis?

A

Cockroaches

49
Q

Taenia taeniaeformis and Capillaria hepatica are parasites of what organ?

A

Liver

50
Q

Taenia serialis is a parasite of which organ?

A

Connective tissue

51
Q

Klossiella muris are parasites of which organ?

A

Kindeys

52
Q

Hepatozoon muris is parasites within what cells?

A

Hepatic cells

53
Q
A