random monoclonal antibodies and their use Flashcards
Infliximab
anti tnf
used in RA and Crohns
rituximab
(anti-CD20): used in non-Hodgkin’s lymphoma and rheumatoid arthritis
cetuximab
(epidermal growth factor receptor antagonist): used in metastatic colorectal cancer and head and neck cancer
trastuzumab
(HER2/neu receptor antagonist): used in metastatic breast cancer
alemtuzumab
(anti-CD52): used in chronic lymphocytic leukaemia
abciximab
(glycoprotein IIb/IIIa receptor antagonist): prevention of ischaemic events in patients undergoing percutaneous coronary interventions
OKT3
used to prevent organ rejection
TOCLIZUMAB
GCA
RA
ALSO side note - methotrexate can be used for remitting disease
RITUXUMAB use
Also used for PMR if steroids don’t work
adalimumab condition used
AS
Golimumab
: psoriasis