Random Metabolism Flashcards

1
Q

TCA occurs where
What type of Phosphorylation
ATP produced

A

Mitochondrial matrix
substrate level
2

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2
Q

ETC occurs where
What type of Phosphorylation
ATP produced

A

Inner Mitochondrial Membrane
Oxidative
32 (G3P shuttle) or 34 (malate-aspartate shuttle)

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3
Q

Fluoride inhibits

which is the enzyme that converts 2-phosphoglycerate to

A

Enolase, PEP

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4
Q

5 cofactors of Pyruvate Dehydrogenase (production of Acetyl-CoA)

A
Pyrophosphate (B1--Thiamine)
FAD (B2--Riboflavin)
NAD (B3--Niacin)
CoA (B5--Pantothenate)
Lipoic acid
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5
Q
  • Also called Cori Cycle
  • Occurs in liver
  • Prevents Lactic Acidosis
  • Lactate–>Glucose
  • Quick ATP production during Anaerobic glycolysis in muscle and erythrocytes
  • Net loss of 4 ATP
  • Amino Acid that is important to this cycle?
A
  • The Lactic Acid Cycle

- Alanine (travels in blood)

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6
Q

Complex IV in ETC contains ___ which requires ____

A

Cytochrome Oxidase

Copper

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7
Q
  • AKA hexose monophosphate shunt
  • Occurs in Cytosol
  • G6P + 2NADP+H20–>R-5-P
  • Rate Limiting Step Enz?
  • Produces___ for ___
A

Pentose Phosphate Pathway

  • G6PD
  • Ribose (nucleotide synth.) & NADPH (FA & Steroid Synth.)
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8
Q
  • Occurs mainly in Liver and Kidneys
  • Converts AA’s–>Glucose or Glycogen when carbs needed
  • Clears Lactic Acid
  • Strict hormonal regulation
A

Gluconeogenesis

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