Random Facts!!! Flashcards
Who developed H-W Equilibrium?
Godfrey Hardy and Wilhelm Wienberg
What percentage of the human genome codes for proteins?
2% out of 3.1 billion nucleotides.
There are roughly 25,000 protein coding genes in the human genome How are there over 100,000 gene products?
Alternative Splicing
ChIP
Chromatin Immuno-precipitation: designed to map protein-DNA interactions and are useful for identifying genes that are regulated by DNA-binding transcription factors.
Necessary Materials:
Adenine Nucleotides
1) DNA bound by formaldehyde
2) DNA extracted from cells and put into small fragments
3) Anti-body added to recognize and get protein
4) Antibody bound by bead for precipitation
rRNA
RITS and RISC
What percentage genes in the human genome code for protein that have no known function?
41%
Open Reading Frames typically do not contain this terrible triplets?
Stop codons
Among people of all racial and ethnic origins, the human genome is nearly the same what is the accepted percent difference in genomic composition between two individuals?
0.1 percent variation
T/F An mRNA sequence must be compared to an open reading frame in order to determine the location of introns
False
What is the name given for a single base-pair difference in human DNA and what does this account for at a phenotypic level?
SNPs; give rise to alleles
Venter’s two haploid genomes contained______
3,213,401 SNPs
Venter’s Two chromosomes were 99.5 percent identical. However, he was still a hetero zygote for what percentage of his genes?
44%
Humans share 80 percent of their genome with what model organisms
Mice!
why does research of the dog genome provide us with advantages for studying heritable human diseases?
Dogs share 400 single-gene disorders, sex chromosome aneuploidies, and behavioral conditions with humans.
How many protein coding genes are there in a human genome?
20,000 protein coding genes
What percentage of the genome is from transpoasable elements and other repetitive sequences?
50%
