Random 4 Flashcards
Adrenaline dose in children 1 month - 5 years
150mcg
Adrenaline dose aged 6- 11 years
300mcg
Adrenaline dose 12-17 years
500mcg
What is hydroxyzine?
Antihistamine used for pruritis
Important safety advice with hydroxyzine
Associated with risk of QT interval prolongation and torsades de points. Should be avoided in elderly as increased risk of s/e (max dose is 50mg in elderly)
What could be given for the management of cough in palliative care?
Morphine
Donepazil side effects?
Dose related cholinergic side effects. Abnormal dreams, agitation, diarrhoea, dizziness, hallucinations, cramps
Memantine should be used in caution in patients with what medical condition?
Epilepsy
Which AEDs cannot be switched between brands?
Phenytoin, carbamazepine, phenobarbital and primodine
Signs of antiepileptic hypersensitivity sydrome
Fever, rash and lymphadenopathy
Liver dysfunction, renal and pulmonary abnormalities
What action should be taken if you suspect antiepileptic hypersensitivity syndrome?
Withdraw AED immediately, do not re-expose
Which antiepileptics are associated with antiepileptic hypersensitivity syndrome?
Carbamazepine, oxacarbazepine, phenytoin and lamotrigine
Which AED is first line for focal seizures?
Carbamazepine or lamotrigine
Which AED is first line in tonic clonic seizures
Sodium valproate or lamotrigine
Which AED is first line in absence seizures
Sodium valproate or ethosuximide
Which AED is first line in myoclonic seziures?
Sodium valproate or levetiracetam or topiramate
Which AED is first line atonic seizures?
Sodium valproate
Which AED may exacerbate parkinsons disease?
Lamotrigine
Nystagmus, diplopia, slurred speech, ataxia, confusion and hyperglycemia as signs of what drug toxicity?
Phenytoin
What monitoring is essential with sodium valproate?
Monitor liver function and FBC
What is the first line treatment for bipolar?
Antipsychotics - olanzapine, quietiapine, or risperidone normally
Which TCA is associated with the lowest incidence of side effects?
Lofepramine and is less dangerous in overdose
Which TCAs are particularly dangerous in over dose?
Amitriptyline, dosulepin
How long after stopping an MAOI can other antidepressants be started?
2 weeks after stopping