Random Flashcards
1
Q
LN follicle
A
B cells
2
Q
LN paracortex
A
T cells
3
Q
LN medullary cords
A
plasma cells
4
Q
LN medullary sinus
A
macrophages
5
Q
How many afferent lymphatic LN vessels
A
many
6
Q
How many efferent lymphatic LN vessel
A
one
7
Q
Where is MALT
A
skin, respiratory, GI tract GALT in intestine (peyers patches in ileum in lamina propria and submucosa) O-MALT in tonsils and adenoids BALT in airways NALT in nose
8
Q
LN drainage - arm and breast
A
axillary LN
9
Q
LN drainage - lat foot
A
popliteal LN
10
Q
LN drainage - thigh
A
superficial inguinal
11
Q
LN drainage - stomach
A
celiac
12
Q
LN drainage -duadenum and jejunum
A
superior mesenteric nodes
13
Q
LN drainage - sigmoid colon
A
colin LN to inferior mesenteric
14
Q
LN drainage - anal canal above pectinate
A
internal iliac
15
Q
LN drainage -anal canal below pectinate
A
superficial inguinal
16
Q
LN drainage -testes
A
paraaortic, because descend during embryology
17
Q
LN drainage - scrotum
A
superficial inguinal
18
Q
LN drainage -right arm and right half of leg
A
right lymphatic duct
19
Q
LN drainage - most of body
A
thoracic duct into L subclavian and internal jugular
20
Q
lymph contains
A
proteins, chylomicrons, , antibodies, milky white
21
Q
LN drainage - cervical LN
A
head and neck
22
Q
LN drainage - hilar LN
A
lungs
23
Q
LN drainage - mediastinal LN
A
trachea and esophagus
24
Q
LN drainage - axillaryLN
A
upper limb, breast, skin above umbilicus
25
LN drainage - celiac LN
liver stomach spleen pancreas upper duodenum
26
LN drainage - superior mesenteric
lower duodenum jejunum ileum colon to splenic flexure
27
LN drainage - inferior mesenteric
colon from splenic flexure to upper rectum
28
LN drainage - internal iliac
lower rectum to anal canal (above pectinate) bladder vagina (middle third) prostate
29
LN drainage - para aortic
testes ovaries kidneys uterus
30
LN drainage - superficial inguinal
anal canal (below pectinate) skin below umbilicus (except popliteal area) scrotum
31
LN drainage - popliteal
dorsolateral foot posterior calf
32
What encodes MHC complexes
HLA loci
33
MHC I loci
HLA - A, B, C
34
MHC II
HLA - DR, DP, DQ
35
HLA A3
hemochromatosis
36
HLA B27
seronegative arthropathies
37
HLA DQ2/DQ8
celiac disease
38
HLA DR2
MS, hay fever, SLE,goodpasture
39
HLA DR3
DMT1SLE graves hashimotos thyroiditis
40
HLA D4
RA DMT1
41
HLA DR5
perncious anemia hashimotos
42
Tx myasthenia gravis
phyxostigmine
| anticholinersterases
43
IL2
proliferation of T cells
44
IL 4
proliferation of B cells, Th0 to Th2
45
IL5
proliferation of B cells
46
IL10
inhibits Th1 and macrophages
47
IL12
Th0 to Th1
48
IFNg
activates macrophages, ihibits Th2
49
Th1 produce
IL2 and IFNg
50
Th2 prodce
IL 2 Il 4 IL 5 IL 10
51
Macrophages and dendritic cytokines
IL12
52
cytokines that activate NK cells
IL 12 IL 2 IFNa IFNb
53
CD 16
binds to constant regions of antibodies and found on NK cells, some macrophages and monocytes and neutrophils
54
anti IgG antibodies
RA
55
ACPA
anti citrullinated protein antibodies
| RA
56
anti centromere
CREST scleroderma
57
anti scl 70
Diffuse scleroderma
58
anti histone
drug induced lupus
59
ANA
antinuclear antibodies
| SLE - not specific
60
anti smith
SLE - more specific
61
anti dsDNA
lupus nephritis
62
anti jo1
polymyositis/dermatomyositis
63
anti SSA
anti Ro
| Sjogren syndrome
64
anti Ro
anti SSA
| Sjogren syndrome
65
anti SSB
anti La
| Sjogren syndrome
66
anti La
anti SSB
| Sjogren syndrome
67
anti U1 RNP
MCTD
68
anti desmoglein
pemphigus vulgaris
69
anti acetylcholine receptor
Myasthenia gravis
70
anti endomysial
anti tissue transglutaminase
| celiac
71
anti tissue transglutaminase
anti endomysial
| celiac
72
anti gliadin
celiac
73
anti mitochondrial
primary biliary cirrhosis
74
anti smooth muscle
autoimmune hepatitis
75
anti glutamate decarboxylase
T1DM
76
anti thyrotropin receptor
graves disease
77
anti thyroid peroxidase
anti TPO
| hasimoto thyroiditis
78
anti thyroglobulin
hashimotos or graves
79
anti basement membrane
goodpasture
80
c ANCA
granulomatosis with polyangitis (wegerners)
81
p ANCA
pauci immune crescentic glomerulonephritis
Churg strauss
microscopic polyangiitis
82
hypersensitivity - rhinitis
1
83
hypersensitivity -acute hemoytic transfusion reaction
2
84
hypersensitivity -arthus reaction
3
85
hypersensitivity -contact dermatitis
4
86
hypersensitivity -hay fever
1
87
hypersensitivity -autoimmune hemolytic anemia
2
88
hypersensitivity -SLE
2/3
89
hypersensitivity - eczema
1
90
hypersensitivity -bullous pemphigoid
2
91
hypersensitivity -erythroblastosis fetalis
2
92
hypersensitivity - PAN
3
93
hypersensitivity - MS
4
94
hypersensitivity -PPD
4
95
hypersensitivity -PSGN
3
96
hypersensitivity - serum sickness
3 on second exposure
97
hypersensitivity - guillan barre
2
98
hypersensitivity -hashimoto
4
99
hypersensitivity - rheumatic fever and scarlet fever
RF - type 2 scarlet fever not from hypersensitivity but from GAS toxins
100
hypersensitivity - goodpasture
2
101
benign heart sounds
split s1
split s2 on inspiration
s3 heart sound in patient < 40 years old
early quiet systolic murmur
102
murmur with widened pulse pressure
aortic regurgitation
103
delayed umbilical cord separation
leukocyte adhesion deificicny type 1
104
retained primary teeth
AD hyper IgEsyndrome or Job syndrome
105
no thymic shadow
digeorge or scid
106
nitroblue tetrazolium test positive
MPO deficiency
107
nitroblue tetrazolium test negative
NADPH deficiency
108
PPV and NPV vary with prevalence
^prevalence -> ^ PPV and decreased NPV
109
Turner syndrome cardiac defects
aortic coarctation and bicuspid aortic valve
110
digeorge syndrome cardiac defects
tetrology of fallot
| interrupted aortic arch
111
Borders of lung pleura
midclavicular - 7th (5-7)
midaxillary - R (upper 10th) L (lower 10th) (7-9)
paravertebral - 12 (9-11)
thoracentesis above - lung injury; below liver or spleen injury
112
nissl substance
RER
113
kinesin
antergrade transport
| ATP - microtubule associated motor protein
114
how does drugs cause ototoxicity
damages outer hair cells (sensitive inner hair cells to specific frequency)
115
signet ring cells
diffuse gastric adenoma (spreads to ovary -krukenber)
| LCIS of breast
116
obligate anerobes lack what
catalase and superoxide dismutase
117
TB in COPD
M kanasaii
118
rice water diarrhea
cholera or VIPoma
119
obligate aerobe bacteria
```
Nagging pests must breath
nocardia
pseudomona
M. tuberculosis
bacillus
```
120
child drinks only goat milk
folate deficiency
121
4 carcinomas that metastasize via blood (hematogenously) instead of lymphatics
1. Renal cell carcinoma
2. Hepatocellular carcinoma
3. Follicular (thyroid) carcinoma
4. Choriocarcinoma
122
honeycomb lung
interstitial fibrosis
123
patient able to point to localize chest pain using one finger
musculoskeletal chest pain
124
chest wall tenderness on palpation
musculoskeletal chest pain
125
rapid onset sharp chest pain in 20 year old, associated with dyspnea
spon pneumothorax
126
chest pain made worse by deep breathing and or motion
musculoskeletal chest pain
127
sternum pain greatly exacerbated by coughing
costotendinitis
