Random Flashcards

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1
Q

What kind of neurons are in the the ventral tegmental area (VTA)?

A

Dopaminergic

Reward, emotion, & motivation
Near substantia nigra & red nucleus

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2
Q

Where do the neurons from the ventral tegmental area (VTA) project?

A

Mesolimbic system
Nucleus accumbens, amygdala, hippocampus, and prefrontal cortex

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3
Q

CSF abnormalities in HSV

A

Lymphocytic predominance: moderate WBCS
Protein: slight elevation
Glucose: normal

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4
Q

What medications can make absence epilepsy worse?

A

Lamotrigine, phenytoin, and carbamazepine/oxcarb

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5
Q

What are typical findings of neurosarcoid?

A
  • Bilateral hilar adenopathy
  • Bilateral cranial nerve palsies
  • Encephalopathy due to a basilar meningoencephalitis
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6
Q

What is augmentation in restless legs syndrome?

A

Symptoms occurring earlier in the day and sometimes spreading from the legs to the arms

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7
Q

What disease are glial cytoplasmic inclusions of alpha synuclein seen?

A

Multiple-system atrophy (MSA)

parkinsonism, ataxia, and autonomic failure

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8
Q

What disease is beta-amyloid seen in?

A

Alzheimer’s disease

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9
Q

What disease is tau seen in?

A

Progressive supranuclear palsy (PSP) Corticobasal degeneration

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10
Q

What disease are TDP-43, tau, and FUS seen in commonly?

A

Frontotemporal dementia

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11
Q

What treatment is likely to improve outcomes in (new onset) Bell’s Palsy?

A

Corticosteroids

If early, adding antiviral w/ steroid might help, but not alone

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12
Q

What is the most common and largest contributor to modifiable stroke risk factors?

A

HTN

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13
Q

What EEG pattern would be seen in Lennox-Gastaut background?

A

2-2.5 spike wave

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14
Q

Kugelberg-Welander syndrome

A

Spinal motor neuron atrophy that has a neurogenic appearance in muscle biopsy specimens

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15
Q

What is the demylination pattern seen in ADEM

acute disseminated encephalomyelitis

A

Perivascular/perivenular pattern of demyelination

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16
Q

In frontotemporal dementia, what cognitive abilities are spared, at least in early disease?

A

Visuospatial and calculation

More pareital location

17
Q

Peripheral nerve hyperexcitability (PNH) (Isaac syndrome) have antibodies to what proteins?

A

CASPR2

18
Q

Peripheral nerve hyperexcitability (PNH) symptoms

A

Muscle cramps and stiffness
Myokymia causing undulating wave-like spontaneous muscle activity

19
Q

What enzyme is effected in Fabry disease?

A

Reduced alpha galactosidase enzyme activity

20
Q

Fabry disease characteritistics

A
  • Painful peripheral neuropathy with autonomic manifestations
  • Typical rash in the lower half of the body
  • Accumulation of glycolipids in the endothelium of cerebral vessels and glomerular arterioles