Rando Path Cards

Question 1

In remodeling, which type of collagen replaces which?

Answer 1

Type I replaces Type III collagen.

Question 2

After months, Type I collagen becomes what?

Answer 2

Fibrosis

Question 3

What lays down Type III collagen?

Answer 3

fibroblasts

Question 4

What does granulation tissue look like?

Answer 4

new tissue growth

it looks red & has blood vessels

Question 5

What do endothelial cells secrete?

Answer 5

platelet activating factor

Question 6

Keloids are formed by an excess of what?

Answer 6

Type III Collagen

Question 7

What are the 2 types of macrophages?

Answer 7

M1: macrophages that are pro-inflammatory
M2: anti-inflammatory; work in wound repair & fibrosis

Question 8

Granulomatous inflammation is a _____ issue. It involves macrophages that are called _________.

Answer 8

chronic issue

giant cells!

Question 9

What is an important transcription factor for TNFalpha & IL-1?

Answer 9

NFKbeta

Question 10

What stimulates the production of Giant cells?

Answer 10

IFMgamma

Question 11

What does interferon gamma stimulate?

Answer 11

granulomatous inflammation

macrophages

Question 12

What does PDGF do?

Answer 12

platelet derived growth factor; involved in angiogenesis