Radiology of IBD/Cancer Flashcards

1
Q

What do you call the inner layer that invaginates in an intussusception? What do you call the outer layer that “receives” and is dilated?

A

Inner invaginating layer is the intussusceptum.

Outer receiving layer that dilates is the intussusceptiens.

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2
Q

What areas are most commonly affected in Crohn’s?

A

Small bowel/colon=55%
Small bowel alone=30%
Colon alone=15%

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3
Q

What are radiographic findings in UC? (6)

A
Granular mucosa
Small nodules/pseudopolyps
ulcers on background 
Tubular configuration colon
Backwash ileitis
Colon cancer
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4
Q

What are radiographic manifestations in Crohn’s on Barium study? (7)

A
Aphthoid ulcers
Mesenteric border ulcers
Sacculation 
Cobblestoning
Wall thickening
Stricture formation
Fistulae
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5
Q

What are radiographic manifestations in Crohn’s on CT? (5)

A
Wall thickening
Mucosal hyperenhancement
Mesenteric fat stranding
Fistulae
Abscess
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6
Q

What is gliadin?

A

Gliadin==> portion of gluten that causes damage to small bowel mucosa

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7
Q

What are histo findings of celiac disease?

A

Loss of intestinal villi
Crypt hyperplasia
Lymphocyte/plasma cell infiltration of LP

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8
Q

What evidence of celiac disease is evident macroscopically?

A

Loss of surface area– Decreased number of folds per inch

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9
Q

What diseases result in acute ischemia of small bowel? (3)

A

Thrombization/embolization of SMA (A fib, valvular heart disease, MI, aneurysm, hyper coagulable states, vacillates, aortic dissection)
Mesenteric vein thrombosis
Low flow states (cardiac failure, trauma, sepsis, drugs)

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10
Q

What are CT findings of ischemia? (6)

A
Dilation and atony 
Bowel wall thickening/target sign
No enhancement (infarction), increased enhancement (vascular permeability)
Pneumatosis, porotomesenteric venous gas
Mesenteric vascular engorgement
Ascites
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11
Q

What is common location of small bowel adenoma/adenocarcinoma?

A

2nd-4th portion of duodenum or proximal jejunum

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12
Q

What are findings of small bowel adenoma/adenocarcinoma

A

Short annular lesion with shelf-like margins, central ulceration or mucosal modularity

Polypoid form less common

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13
Q

What is common location of small bowel carcinoid tumors?

A

Distal ileum

30% multifocal with extension beyond bowel wall

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14
Q

What are findings of small bowel carcinoid tumors?

A

Small smooth sessile polypoid lesion in distal ileum
Bowel “tethered” at tumor site
Speculated calcified mesenteric mass
Hypervascular masses in liver/ larger mets heterogenous

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15
Q

Primary small bowel lymphoma: location

A

Distant small bowel
Can be solitary or multiple
Lymphadenopathy confined to small bowel mesentery

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16
Q

What are the macroscopic types of Small bowel lymphoma? (3)

A

Focal area with smooth thick folds
Long annular lesion
Cavitary mass

17
Q

Why does bowel dilate in lymphoma? (aneurysmal dilatation?

A

Because of invasion of muscular propria

18
Q

Diverticular disease: what are two findings

A

Multiple small sacs (herniations mucosa/submucosa at sites of penetrating arterioles

Myochosis: Alteration of circular/longitudinal muscle layers due to elastin deposits

19
Q

Why do diverticula only bleed into the lumen?

A

Because as diverticulum push into adjacent arteriole, eccentric damage to vessel occurs on side of diverticulum. When the vessel ruptures it does so into th lumen of the diverticulum

20
Q

What is a hyperplastic polyp? How does it appear histologically?

A

Alteration in maturation of epithelium

Microscopically observe elongated crypts lined by serrated epithelium of intermediate/goblet cells

21
Q

How common are polyps? Where are they most likely to appear?

A

Hyperplastic polyps can be seen in 75% of pts over 40yo

They occur most often in rectum (rather than colon)

22
Q

Which factor determines malignant potential of adenoma?

Size or architecture

A

Size is largest determinant

23
Q

What is most extramucosal tumor in colon?

Where is it most commonly found?

A

Lipoma: an encapsulated mass of mature fat

90% in submucosa
70% are in right colon