GI Radiology Flashcards
Pathogenesis of GERD: What increases the frequency of GER? (2)
Decreased LES tone
Multiple transient LES relaxations
What are the two main factors in pathogenesis of GERD?
Increased frequency of GER
Increased duration of GER
Increased acidity of refluxate
Resistance of mucosa
What can increase the duration of GER?
Abnormal motility (i.e from scleroderma)
What can increase the acidity of refluxate?
ZES (increased acid) Billroth II (bile)
What increases the resistance of mucosa?
Age
Debilitation
What are the clinical findings of GERD? (4)
Heartburn/regurg
Epigastric/RUQ pain
Upper GI bleeding
Dysphagia
How do esophageal ulcers from GERD present on imaging?
Tiny stellate/punctate lit up areas
What are two the most common causes of infectious esophagitis?
1st: Candida
2nd: Herpes
What are symptoms of candida esophagitis? What is the treatment of choice?
Dysphagia or odynophagia
Treat with fluconazole (an antifungal)
How does esophageal candidiasis present on contrast imaging?
Multiple plaque-like lesions
If severe, fulminate “shaggy” looking
How does herpes esophagitis present? What’s the recommended treatment?
Dysphagia or odynophagia
Treat with acyclovir
How does herpes esophagitis present on imaging?
Multiple tiny punctate ulcers filled with barium
How does CMV esophagitis present on imaging? How do you treat it?
Giant barium ulcers with thin adenomatous ring
Gancyclovir
Should follow up be done with suspected CMV esophagitis?
Yes, do endoscopy– treatment is toxic to BM, and esophagitis can be caused by HIV
How does HIV esophagitis present?
What is recommended treatment?
Odynophagia, giant ulcers with presence of palatal ulcers, maculopapular rash
Treat with steroids