Radiation Procedures - Lymphoma Flashcards
Lymph node primary functions: (2)
Filter organs
Produce immune cells (i.e. lymphocytes)
2 types of lymphocytes:
B cells & T cells
B Cell function:
create antibodies
T Cell function:
Destroy pathogens
Hodgkin lymphoma typically starts: (general area of body)
Upper body
Ann Arbor staging used for:
Hodgkins & Non-Hodgkins
Stages 1 & 2 for Hodgkins are located only in areas ___.
Above the diaphragm
Stages 3 & 4 for Hodgkins indicates that ___.
It has spread below diaphragm
Subtypes of Classical Hodgkins: (4)
Nodular sclerosing
Mixed cellularity
Lymphocyte-rich
Lymphocyte-depleted
Hodgkins Stage A indicates:
No symptoms (Asymptomatic)
Hodgkins Stage B indicates:
- Symptoms?
Any of the following symptoms:
fever
night sweats
10% weight loss w/in 6 months
What virus increases risk for Hodgkins?
EBV
Does Hodgkins A or B have a worse prognosis?
B
Gold standard care for chemo for Hodgkins is a combo of:
ABVD:
Adriamyocin
Bleomyocin
Vinblastin
Decarbazine
Original chemo combo for Hodgkins:
MOPP:
Nitrogen mustard - M
Vincristine Sulfate (Oncoven) - O
Procarbazine - P
Prednisone - P
What cell differentiates Hodgkins from Non-Hodgkins Lymphoma?
Reed-Sternberg Cell
Most common type of Hodgkins Lymphoma:
Classic
Hodgkins mets to: (4)
Liver
Lung
Bone
Bone Marrow
Fields for Hodgkins: (2)
Mantle
Inverted Y
What is total nodal irradiation?
Both Mantle and Inverted Y
Which Hodgkins field treats nodes in neck, chest and axilla?
Mantle
Which Hodgkins field treats nodes in abdomen, pelvis, and spleen?
Inverted Y
3 common locations for Non-Hodgkins:
Lymph Nodes
Waldyer’s Ring
GI Tract/Peyer’s Patches
Chemo combo for Non-Hodgkins:
CHOP
Cyclophosphamide
Vincristine
Doxyrubicin
Prednisone
Most common Non-Hodgkins Lymphoma (B-Cell or T-Cell)?
B-Cell
Non-Hodgkins Lymphoma staging system:
- based on what?
Lugano Classification
- Ann Arbor
Non-Hodgkins mets to: (4)
Liver
Lungs
Bone (Nappi said Brain in video - double check)
Bone Marrow
