Radiation Procedures - Lymphoma Flashcards

1
Q

Lymph node primary functions: (2)

A

Filter organs
Produce immune cells (i.e. lymphocytes)

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2
Q

2 types of lymphocytes:

A

B cells & T cells

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3
Q

B Cell function:

A

create antibodies

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4
Q

T Cell function:

A

Destroy pathogens

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5
Q

Hodgkin lymphoma typically starts: (general area of body)

A

Upper body

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6
Q

Ann Arbor staging used for:

A

Hodgkins & Non-Hodgkins

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7
Q

Stages 1 & 2 for Hodgkins are located only in areas ___.

A

Above the diaphragm

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8
Q

Stages 3 & 4 for Hodgkins indicates that ___.

A

It has spread below diaphragm

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9
Q

Subtypes of Classical Hodgkins: (4)

A

Nodular sclerosing
Mixed cellularity
Lymphocyte-rich
Lymphocyte-depleted

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10
Q

Hodgkins Stage A indicates:

A

No symptoms (Asymptomatic)

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11
Q

Hodgkins Stage B indicates:
- Symptoms?

A

Any of the following symptoms:
fever
night sweats
10% weight loss w/in 6 months

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12
Q

What virus increases risk for Hodgkins?

A

EBV

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13
Q

Does Hodgkins A or B have a worse prognosis?

A

B

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14
Q

Gold standard care for chemo for Hodgkins is a combo of:

A

ABVD:
Adriamyocin
Bleomyocin
Vinblastin
Decarbazine

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15
Q

Original chemo combo for Hodgkins:

A

MOPP:
Nitrogen mustard - M
Vincristine Sulfate (Oncoven) - O
Procarbazine - P
Prednisone - P

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16
Q

What cell differentiates Hodgkins from Non-Hodgkins Lymphoma?

A

Reed-Sternberg Cell

17
Q

Most common type of Hodgkins Lymphoma:

A

Classic

18
Q

Hodgkins mets to: (4)

A

Liver
Lung
Bone
Bone Marrow

19
Q

Fields for Hodgkins: (2)

A

Mantle
Inverted Y

20
Q

What is total nodal irradiation?

A

Both Mantle and Inverted Y

21
Q

Which Hodgkins field treats nodes in neck, chest and axilla?

A

Mantle

22
Q

Which Hodgkins field treats nodes in abdomen, pelvis, and spleen?

A

Inverted Y

23
Q

3 common locations for Non-Hodgkins:

A

Lymph Nodes
Waldyer’s Ring
GI Tract/Peyer’s Patches

24
Q

Chemo combo for Non-Hodgkins:

A

CHOP
Cyclophosphamide
Vincristine
Doxyrubicin
Prednisone

25
Q

Most common Non-Hodgkins Lymphoma (B-Cell or T-Cell)?

A

B-Cell

26
Q

Non-Hodgkins Lymphoma staging system:
- based on what?

A

Lugano Classification
- Ann Arbor

27
Q

Non-Hodgkins mets to: (4)

A

Liver
Lungs
Bone (Nappi said Brain in video - double check)
Bone Marrow