Rad bio test 2 Flashcards
1st deterministic effects of radiation
- acute rad syndrome
- hematopoietic
- gastrointestinal
- cns
2nd deterministic effects of radiation
- local tissue damage
- skin
- gonads
- extremities
3rd deterministic effects of radiation
- hematologic depression
4th deterministic effects of radiation
- cytogenetic damage
1st stochastic effects of radiation
- leukemia
2nd stochastic effects of radiation
- other malignant disease
- bone cancer
- lung cancer
- thyroid cancer
- breast cancer
3rd stochastic effects of radiation
- local tissue damage
- skin
- gonads
- eyes
4th stochastic effects of radiation
- shortening of life span
5th stochastic effects of radiation
- genetic damage
- cytogenetic damage
- doubling dose
- genetically significant dose
effects of fetal irradiation
prenatal death neonatal death congenital malformation childhood malignancy diminished growth and development
deterministic effect
radiation response increase in severity with increasing dose ( within days)
stochastic effect
radiation response increasing with increasing radiation dose ( months or years)
radiobiology
study of effects of ionizing radiation on biologic effects
atomic composition of body
60% hydrogen 25.7% oxygen 10.7% carbon 2.4% nitrogen .2% calcium .1% phosphorus .1% sulfur .8% trace elements
robert hooke
first named the cell as the biologic building block 1665
anton and leeuwenkoek
1673 described the living cell through microscopic observation
schneider and schwann
all plants and animals the cell is the basic fundamental unit 1838 ( Cell Theory)
Watson and Crick
1953 DNA as the genetic substance of cells
molecule composition
80% water 15%protein 2% lipid 1% carbohydrates 1% nucleic acid
macromolecules
very large molecules that consist sometimes of hundred of thousand of thousands of atoms
organic molecules
proteins, lipids, carbohydrates
life supporting and contains carbon
catabolism
breakdown into smaller units of macromolecules
anabolism
production of large molecules from small
metabolism
anabolism and catabolism collectively
protein
consists of amino acids and peptide bonds
protein synthesis
22 amino acids, the metabolic production of protein
enzymes
molecules that are necessary in small quantities to allow biochemical reactions
hormomes
molecules that exercise regulatory control over some body functions such as growth and development
endocrine glands
pituitary, adrenal, thyroid, parathyroid, pancreas, and gonads
antibodies
primary defense mechanism of the body against infection and disease
antigen
infectious agent
lipids
glycerol and fatty acids
composed od CHO
present in all tissues and is structural components of cell membranes
(thermal insulator)
carbohydrates
(saccharides) provide fuel for cell metabolism
purines
adenine and guanine
pyrimidines
thymine and cytosine
endoplasmic recticulum
channel that allows the nucleus to communicate to the cytoplasm