RA Flashcards

1
Q

DMARDs should be started within ……………… of diagnosis

A

3 months

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2
Q

If RA is suspected what treatment should begin

A

NSAIDs

+/- PPI and paracetamol

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3
Q

NSAID anti-inflammatory effect can take…………

and analgesic effect …………………..

A

3 weeks

1 week

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4
Q

Joint destruction is irreversible and only eased by…..

A

joint replacement

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5
Q

Choice of NSAID dependent on

A
efficacy
tox
other meds
other disease
age
renal and liver func
cost
Rxer preference
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6
Q

Monitoring in RA

A

pain

range of movement

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7
Q

Methotrexate is given with

A

folic acid - to prevent side-effects

methotrexate is weekly!

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8
Q

Methotrexate effects ……….. cells

A

All rapidly dividing cells

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9
Q

Methotrexate counselling

A

Weekly
alcohol (hepatic cirrhosis)
contraception

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10
Q

Do DMARDs have analgesic effect?

A

No

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11
Q

What might you monitor in serum levels?

A

ESR - erythrocyte sedimentation rate

CRP

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12
Q

In a flare with normal DMARD therapy you might

A

add a second DMARD

methotrexate +/- sulfasalazine/ciclosporin

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