RA

Question 1

DMARDs should be started within ……………… of diagnosis

Answer 1

3 months

Question 2

If RA is suspected what treatment should begin

Answer 2

NSAIDs

+/- PPI and paracetamol

Question 3

NSAID anti-inflammatory effect can take…………

and analgesic effect …………………..

Answer 3

3 weeks

1 week

Question 4

Joint destruction is irreversible and only eased by…..

Answer 4

joint replacement

Question 5

Choice of NSAID dependent on

Answer 5

efficacy
tox
other meds
other disease
age
renal and liver func
cost
Rxer preference

Question 6

Monitoring in RA

Answer 6

pain

range of movement

Question 7

Methotrexate is given with

Answer 7

folic acid - to prevent side-effects

methotrexate is weekly!

Question 8

Methotrexate effects ……….. cells

Answer 8

All rapidly dividing cells

Question 9

Methotrexate counselling

Answer 9

Weekly
alcohol (hepatic cirrhosis)
contraception

Question 10

Do DMARDs have analgesic effect?

Answer 10

No

Question 11

What might you monitor in serum levels?

Answer 11

ESR - erythrocyte sedimentation rate

CRP

Question 12

In a flare with normal DMARD therapy you might

Answer 12

add a second DMARD

methotrexate +/- sulfasalazine/ciclosporin