Quizzes and stuff Flashcards
1
Q
PK equations are used in what situations? (5)
A
- They have a narrow therapeutic range i.e. the effective level is close to the toxic level.
- There is no clear observable endpoint to therapeutic success.
- There is an unpredictable dose: response relationship
- Toxicity or lack of effect may be dangerous.
- Toxic side effects may be similar to characteristics of the disease being treated.