quizlets Flashcards
The first step in fatty acid synthesis involves (A) Acetyl CoA carboxylase (B) 3 Hydroxyl CoA dehydrogenase (C) Acetyl dehydrogenase (D) Pyruvate kinase
(A) Acetyl CoA carboxylase
Enzymes that move a molecular group from one molecule to another are known as - (A) Ligases (B) Oxido-reductases (C) Transferases (D) Dipeptidases
(C) Transferases
Mechanism by which pyruvate cytosol is transported to mitochondria is - (A) Chloride antiport (B) Proton symport (C) ATP dependent antiport (D) Facilitated uniport
(B) Proton symport
Which of the following statement about thiamine is true?
(A) It is a co-enzyme of lactate dehydrogenase
(B) Its deficiency is associated with scurvy’
(C) Its co-enzyme function is done by thiamine monophosphate
(D) It is co-enzyme for pyruvate dehydrogenase and on-ketoglutarate dehydrogenase
(D) It is co-enzyme for pyruvate dehydrogenase and on-ketoglutarate dehydrogenase
In Beriberi, which enzyme activity is measured? (A) Transketolase (B) Transaminase (C) Decarboxylase (D) Deaminase
(A) Transketolase
Creatinine is formed from: (A) Arginine (B) Lysine (C) Leucine (D) Histamine
(A) Arginine
Serine proteases:
(A) Hydrolyze peptide bonds involving carboxyl groups of serine residues
(B) Are characterized by having several active sites per molecule each containing a serine residue
(C) Are inactivated by reaching with one molecule of di-isopropyl-fluorophosphate per molecule of protein
(D) Are Exopeptidase
(B) Are characterized by having several active sites per molecule each containing a serine residue
The parameter used as an index of lipid peroxidation is the level of: (A) Ascorbic acid (B) Hydrogen peroxide (C) Malondialdehyde (D) Volatile fatty acids
(C) Malondialdehyde
Features of Vitamin C deficiency is due to defect of which enzyme? (A) Lysyl hydroxylase (B) Lysyl oxidase (C) Procollagen (D) Peptidase
(A) Lysyl hydroxylase
All the following degradation product of Glycine, except: (A) Serine (B) Oxalates (C) Pyruvates (D) Ornithine
(D) Ornithine
In competitive inhibition the relation Km and Vmax is one of the following: (A) Km and Vmax are the same (B) Km increases and Vmax is the same (C) Km decreases and Vmax increases (D) Km and Vmax decreases
(B) Km increases and Vmax is the same
Enzyme deficient in Marfan's syndrome: (A) Cystathionine beta synthase (B) Elastase type II (C) Lysyl oxidase (D) Collagenase (E) None of the above
(E) None of the above
*Cystathionine beta synthase
It catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine:
Porphyrias absorb light in the wavelength of: (A) 340nm (B) 400nm (C) 540nm (D) 67Onm
(B) 400nm
All of the following is/are extracellular matrix protein, except? (A) Collagen (B) Laminin (C) Fibronectin (D) Integrin (E) Elastin
(D) Integrin
What is the most acute effect of smoking cessation?
(A) Shift of oxyhemoglobin curve to the right
(B) Increased ciliary function
(C) Decreased mucous production
(D) Decreased incidence of post operative pneumonia
(A) Shift of oxyhemoglobin curve to the right
Enzymes not important in testosterone biosynthesis: (A) 5-alpha reductase (B) Delta 5-4 isomerase (C) 18 hydroxylase (D) Alpha hydroxylase
(C) 18 hydroxylase
The rate limiting enzyme in glycolysis: (A) Glucose 6-dehydrogenase (B) Phosphofructokinase 1 (C) Glucokinase (D) Pyruvate kinase I
(B) Phosphofructokinase 1
At isoelectric pH protein:
(A) Have Net charge 0
(B) Are positively charged
(C) Are negatively charged
(A) Have Net charge 0
Heart uses one of following as energy source during starvation: (A) Glucose (B) Acetoacetate (C) Fats (D) Proteins
C) Fats
Vitamin C is present in largest amount in the body in: (A) Eye (B) Kidneys (C) Testes (D) Adrenal cortex (E) Pancreas
(D) Adrenal cortex
Ehrlich's test is done to detect: (A) Urinary amylase (B) Urinary cystine (C) Abnormal porphyrin (D) Urobilinogen
(D) Urobilinogen
What is the connecting link between urea cycle and TCA cycle? (A) Fumarate (B) Succinate (C) Oxaloacetate (D) Arginine succinate
(A) Fumarate
Excessive ultraviolet (UV) radiation is harmful to life. The damage caused to the biological systems by ultraviolet radiation is by: (A) Inhibition of DNA synthesis (B) Formation of thymidine dimers (C) Ionization (D) DNA fragmentation
(B) Formation of thymidine dimers
Squalene" is the intermediate product during synthesis of: (A) VLDL (B) Cholesterol (C) Tachysterol (D) Lanosterol
(B) Cholesterol
Which of the following statements about facilitated diffusion is true?
(A) It is a form of active transport
(B) It requires a carrier protein
(C) Rate of transport is proportionate to the concentration gradient
(D) Requires creatine phosphate
(B) It requires a carrier protein
Respiratory distress syndrome in premature infants is due to inadequate secretion of which one of the following lipids? (A) Dipalmitoyl phosphatidylcholine (B) Sphingomyelin (C) Cholesterol (D) Phosphatidylinositol
(A) Dipalmitoyl phosphatidylcholine
Apart from occurring in nucleic acids pyrimidines are also found in: (A) Theophylline (B) Theobromine (C) Flavin mononucleotide (D) Thiamine
(D) Thiamine
During standard plasma electrophoresis a protein that moves ahead of albumin is: (A) Fibrinogen (B) Alpha feto protein (C) Hemopexin (D) Retinol binding protein
(D) Retinol binding protein
Glycosphingolipid is made up of the following, except: (A) Glucose (B) Glycerol (C) Sphingosine (D) Fatty acids
(B) Glycerol
Andersen disease is due to deficiency of: (A) Debranching enzyme (B) Branching enzyme (C) Myophosphorylase (D) Acid maltase
(B) Branching enzyme
Function of ubiquitin in the cells is: (A) Protein degradation (B) Election transport chain (C) Endocytosis (D) Acute inflammation
(A) Protein degradation
Transport of ADP in and ATP out of mitochondria is inhibited by: (A) Atractyloside (B) Oligomycin (C) Rotenone (D) Cyanide
(A) Atractyloside
HMP shunt is of great importance in cellular metabolism because it produces: (A)ATP (B) ADP (C) Acetyl CoA (D) NADPH
(D) NADPH
Porphobilinogen in urine produces pink colour with: (A) Fouchet's reagent (B) Benedict's reagent (C) Sodium nitroprusside (D) Ehrlich's aldehyde reagent
(D) Ehrlich’s aldehyde reagent
Maximum carbohydrate concentration in strict vegetarian diet present are the following, except: (A) Amylase (B) Maltose (C) Fructose (D) Glycogen
(A) Amylase
The regulatory enzyme in the biosynthetic pathway of Cholesterol is:
(A) Hydroxymethyl glutaryl co. A synthetase
(B) Hydroxymethyl glutaryl coA reductase
(C) Mevalonate Kinase
(D) Isopentenyl l pyrophospho isomerase
(B) Hydroxymethyl glutaryl coA reductase
Marker of Golgi apparatus: (A) Galactosyl transferase (B) Acetyl CoA synthase (C) Pyruvate kinase (D) Malonyl Co A
(A) Galactosyl transferase
Flexibility of protein depends on: (A) Glycine (B) Tryptophan (C) Phenylalanine (D) Histidine
(A) Glycine
C17 H29 COOH is formula of: (A) Linoleic acid (B) Linolenic acid (C) Arachidonic acid (D) Clupanodonic acid
(B) Linolenic acid
Which of the following is a membrane-bound enzyme that catalyzes the formation of cyclic AMP from ATP? (A) Tyrosine kinase (B) Polymerase (C) ATP synthase (D) Adenylate cyclase
(D) Adenylate cyclase
Nicotinamide is derived from: (A) Histidine (B) Methionine (C) Tryptophan (D) Phenylalanine
(C) Tryptophan
Muscle is the major biochemical transducer because it
(A) Converts potential energy into kinetic energy
(B) Converts kinetic energy to potential energy
(C) Converts thermal energy to kinetic energy
(D) Converts thermal energy to potential energy
(A) Converts potential energy into kinetic energy
Acetyl CoA can be converted into all of the following, except: (A) Glucose (B) Fatty Acids (C) Cholesterol (D) Ketone bodies
(A) Glucose
Explanation: Once carbons are in the form of Acetyl CoA they cannot be converted to glucose. This is because Acetyl CoA cannot be converted to pyruvate on a net basis since the carbon backbone of Acetyl CoA is lost in the TCA cycle as CO2
