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quizlets Flashcards

1
Q 
The first step in fatty acid synthesis involves
(A) Acetyl CoA carboxylase
(B) 3 Hydroxyl CoA dehydrogenase
(C) Acetyl dehydrogenase
(D) Pyruvate kinase
A

(A) Acetyl CoA carboxylase

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2
Q 
Enzymes that move a molecular group from one molecule to another are known as -
(A) Ligases
(B) Oxido-reductases
(C) Transferases
(D) Dipeptidases
A

(C) Transferases

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3
Q 
Mechanism by which pyruvate cytosol is transported to mitochondria is -
(A) Chloride antiport
(B) Proton symport
(C) ATP dependent antiport
(D) Facilitated uniport
A

(B) Proton symport

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4
Q

Which of the following statement about thiamine is true?
(A) It is a co-enzyme of lactate dehydrogenase
(B) Its deficiency is associated with scurvy’
(C) Its co-enzyme function is done by thiamine monophosphate
(D) It is co-enzyme for pyruvate dehydrogenase and on-ketoglutarate dehydrogenase

A

(D) It is co-enzyme for pyruvate dehydrogenase and on-ketoglutarate dehydrogenase

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5
Q 
In Beriberi, which enzyme activity is measured?
(A) Transketolase
(B) Transaminase
(C) Decarboxylase
(D) Deaminase
A

(A) Transketolase

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6
Q 
Creatinine is formed from:
(A) Arginine
(B) Lysine
(C) Leucine
(D) Histamine
A

(A) Arginine

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7
Q

Serine proteases:
(A) Hydrolyze peptide bonds involving carboxyl groups of serine residues
(B) Are characterized by having several active sites per molecule each containing a serine residue
(C) Are inactivated by reaching with one molecule of di-isopropyl-fluorophosphate per molecule of protein
(D) Are Exopeptidase

A

(B) Are characterized by having several active sites per molecule each containing a serine residue

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8
Q 
The parameter used as an index of lipid peroxidation is the level of:
(A) Ascorbic acid
(B) Hydrogen peroxide
(C) Malondialdehyde
(D) Volatile fatty acids
A

(C) Malondialdehyde

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9
Q 
Features of Vitamin C deficiency is due to defect of which enzyme?
(A) Lysyl hydroxylase
(B) Lysyl oxidase
(C) Procollagen
(D) Peptidase
A

(A) Lysyl hydroxylase

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10
Q 
All the following degradation product of Glycine, except:
(A) Serine
(B) Oxalates
(C) Pyruvates
(D) Ornithine
A

(D) Ornithine

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11
Q 
In competitive inhibition the relation Km and Vmax is one of the following:
(A) Km and Vmax are the same
(B) Km increases and Vmax is the same
(C) Km decreases and Vmax increases
(D) Km and Vmax decreases
A

(B) Km increases and Vmax is the same

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12
Q 
Enzyme deficient in Marfan's syndrome:
(A) Cystathionine beta synthase
(B) Elastase type II
(C) Lysyl oxidase
(D) Collagenase
(E) None of the above
A

(E) None of the above

*Cystathionine beta synthase

It catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine:

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13
Q 
Porphyrias absorb light in the wavelength of:
(A) 340nm
(B) 400nm
(C) 540nm
(D) 67Onm
A

(B) 400nm

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14
Q 
All of the following is/are extracellular matrix protein, except?
(A) Collagen
(B) Laminin
(C) Fibronectin
(D) Integrin
(E) Elastin
A

(D) Integrin

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15
Q

What is the most acute effect of smoking cessation?
(A) Shift of oxyhemoglobin curve to the right
(B) Increased ciliary function
(C) Decreased mucous production
(D) Decreased incidence of post operative pneumonia

A

(A) Shift of oxyhemoglobin curve to the right

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16
Q 
Enzymes not important in testosterone biosynthesis:
(A) 5-alpha reductase
(B) Delta 5-4 isomerase
(C) 18 hydroxylase
(D) Alpha hydroxylase
A

(C) 18 hydroxylase

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17
Q 
The rate limiting enzyme in glycolysis:
(A) Glucose 6-dehydrogenase
(B) Phosphofructokinase 1
(C) Glucokinase
(D) Pyruvate kinase I
A

(B) Phosphofructokinase 1

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18
Q

At isoelectric pH protein:
(A) Have Net charge 0
(B) Are positively charged
(C) Are negatively charged

A

(A) Have Net charge 0

19
Q 
Heart uses one of following as energy source during starvation:
(A) Glucose
(B) Acetoacetate
(C) Fats
(D) Proteins
A

C) Fats

20
Q 
Vitamin C is present in largest amount in the body in:
(A) Eye
(B) Kidneys
(C) Testes
(D) Adrenal cortex
(E) Pancreas
A

(D) Adrenal cortex

21
Q 
Ehrlich's test is done to detect:
(A) Urinary amylase
(B) Urinary cystine
(C) Abnormal porphyrin
(D) Urobilinogen
A

(D) Urobilinogen

22
Q 
What is the connecting link between urea cycle and TCA cycle?
(A) Fumarate
(B) Succinate
(C) Oxaloacetate
(D) Arginine succinate
A

(A) Fumarate

23
Q 
Excessive ultraviolet (UV) radiation is harmful to life. The damage caused to the biological systems by ultraviolet radiation is by:
(A) Inhibition of DNA synthesis
(B) Formation of thymidine dimers
(C) Ionization
(D) DNA fragmentation
A

(B) Formation of thymidine dimers

24
Q 
Squalene" is the intermediate product during synthesis of:
(A) VLDL
(B) Cholesterol
(C) Tachysterol
(D) Lanosterol
A

(B) Cholesterol

25
Q

Which of the following statements about facilitated diffusion is true?
(A) It is a form of active transport
(B) It requires a carrier protein
(C) Rate of transport is proportionate to the concentration gradient
(D) Requires creatine phosphate

A

(B) It requires a carrier protein

26
Q 
Respiratory distress syndrome in premature infants is due to inadequate secretion of which one of the following lipids?
(A) Dipalmitoyl phosphatidylcholine
(B) Sphingomyelin
(C) Cholesterol
(D) Phosphatidylinositol
A

(A) Dipalmitoyl phosphatidylcholine

27
Q 
Apart from occurring in nucleic acids pyrimidines are also found in:
(A) Theophylline
(B) Theobromine
(C) Flavin mononucleotide
(D) Thiamine
A

(D) Thiamine

28
Q 
During standard plasma electrophoresis a protein that moves ahead of albumin is:
(A) Fibrinogen
(B) Alpha feto protein
(C) Hemopexin
(D) Retinol binding protein
A

(D) Retinol binding protein

29
Q 
Glycosphingolipid is made up of the following, except: 
(A) Glucose
(B) Glycerol
(C) Sphingosine
(D) Fatty acids
A

(B) Glycerol

30
Q 
Andersen disease is due to deficiency of:
(A) Debranching enzyme
(B) Branching enzyme
(C) Myophosphorylase
(D) Acid maltase
A

(B) Branching enzyme

31
Q 
Function of ubiquitin in the cells is:
(A) Protein degradation
(B) Election transport chain
(C) Endocytosis
(D) Acute inflammation
A

(A) Protein degradation

32
Q 
Transport of ADP in and ATP out of mitochondria is inhibited by:
(A) Atractyloside
(B) Oligomycin
(C) Rotenone
(D) Cyanide
A

(A) Atractyloside

33
Q 
HMP shunt is of great importance in cellular metabolism because it produces:
(A)ATP
(B) ADP
(C) Acetyl CoA
(D) NADPH
A

(D) NADPH

34
Q 
Porphobilinogen in urine produces pink colour with:
(A) Fouchet's reagent
(B) Benedict's reagent
(C) Sodium nitroprusside
(D) Ehrlich's aldehyde reagent
A

(D) Ehrlich’s aldehyde reagent

35
Q 
Maximum carbohydrate concentration in strict vegetarian diet present are the following, except:
(A) Amylase
(B) Maltose
(C) Fructose
(D) Glycogen
A

(A) Amylase

36
Q

The regulatory enzyme in the biosynthetic pathway of Cholesterol is:
(A) Hydroxymethyl glutaryl co. A synthetase
(B) Hydroxymethyl glutaryl coA reductase
(C) Mevalonate Kinase
(D) Isopentenyl l pyrophospho isomerase

A

(B) Hydroxymethyl glutaryl coA reductase

37
Q 
Marker of Golgi apparatus:
(A) Galactosyl transferase
(B) Acetyl CoA synthase
(C) Pyruvate kinase
(D) Malonyl Co A
A

(A) Galactosyl transferase

38
Q 
Flexibility of protein depends on: 
(A) Glycine
(B) Tryptophan
(C) Phenylalanine
(D) Histidine
A

(A) Glycine

39
Q 
C17 H29 COOH is formula of:
(A) Linoleic acid
(B) Linolenic acid
(C) Arachidonic acid
(D) Clupanodonic acid
A

(B) Linolenic acid

40
Q 
Which of the following is a membrane-bound enzyme that catalyzes the formation of cyclic AMP from ATP?
(A) Tyrosine kinase
(B) Polymerase
(C) ATP synthase
(D) Adenylate cyclase
A

(D) Adenylate cyclase

41
Q 
Nicotinamide is derived from:
(A) Histidine
(B) Methionine
(C) Tryptophan
(D) Phenylalanine
A

(C) Tryptophan

42
Q

Muscle is the major biochemical transducer because it
(A) Converts potential energy into kinetic energy
(B) Converts kinetic energy to potential energy
(C) Converts thermal energy to kinetic energy
(D) Converts thermal energy to potential energy

A

(A) Converts potential energy into kinetic energy

43
Q 
Acetyl CoA can be converted into all of the following, except:
(A) Glucose
(B) Fatty Acids
(C) Cholesterol
(D) Ketone bodies
A

(A) Glucose

Explanation: Once carbons are in the form of Acetyl CoA they cannot be converted to glucose. This is because Acetyl CoA cannot be converted to pyruvate on a net basis since the carbon backbone of Acetyl CoA is lost in the TCA cycle as CO2

Biochem (9 decks)

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