Quiz 8.13.21

Question 1

Where do superficial lymph nodes drain

Answer 1

Waldeyer’s ring, at the junction between head and neck.

Question 2

Occipital lymph nodes

Answer 2

From occipital area

Question 3

Mastoid lymph node

Answer 3

Posterior neck, upper ear, scalp

Question 4

preauricular lymph node

Answer 4

superficial face, temporal region

Question 5

parotid lymph

Answer 5

lateral face/scalp

Question 6

submental lymph

Answer 6

chin/lower lip

Question 7

submandibular lymph

Answer 7

mouth, face inferior, eye

Question 8

buccal lymph

Answer 8

nose, cheek

Question 9

superficial cervical

Answer 9

anterior neck

Question 10

Components of Hx Present Illness

Answer 10

Location, Quality, Severity, Timing, Context, Modifying factors, Associated Sxs
Lightning Quick Sprinting Always Turns Calves Massive

Question 11

Centor meaning

Answer 11

Cough Absent/ inability
Exudate (oozing white patches)
Nodes (tender lymph)
Temperature (fever)
OR (<15 or >44)

Question 12

Conditions for Centor

Answer 12

1 pt per indication, except -1 if age >44.
<2 means unlikely strep
2-3 means give culture and treat as appropriate.
+3 means rapid test, strep probable.

Question 13

Clinical pres. of Rhinoviruses, virology

Answer 13

Virology:
No envelope, +sense ssRNA,
Clin pres:
Most common upper resp infec, common colds,

Question 14

Virology, clinical pres of influenza

Answer 14

-sense ssRNA, enveloped, fragmented genome, rep. in nucleus.
Abrupt onset, GI, pulmonary comp,

Question 15

Virology, clinical pres of coronaviruses

Answer 15

+Sense ssRNA, enveloped, 2nd most common for colds,

Question 16

Paramyxoviruses

Answer 16

-sense ssRNA, upper resp. , not pathologic in other regions, easily transmitted.

Question 17

Oseltamivir

Answer 17

Tamiflu,
Neuraminidase,
Prevents new virons from getting out of cell. GI sides.

Question 18

Baloxavir

Answer 18

New,

Polymerase endonuclease, prevents RNA polymerase function. Very few sides

Question 19

Amantidine/ rimantidine

Answer 19

No longer in vogue, CNS sides, M2 inhibitor, prevents uncoating of virus.

Question 20

Flu complications for children vs adults

Answer 20

Adults more likely to have inflammation of organs, children more likely to develop pneumonia, organ dysfunciton

Question 21

Antipyretics not for children

Answer 21

Aspirin: May lead to Reye’s (Convulsions/ Unconsciousness triggered in children with preexisting fatty acid oxidation disorder)
Naproxen: Overdose

Question 22

Population health

Answer 22

Health outcomes of a group

Question 23

Public Health

Answer 23

What we choose to do as a society to promote healthy lives

Question 24

Population medicine

Answer 24

The study of design, delivery, coordination, and economics of high quality HC services.

Question 25

4 functions of secreted antibodies

Answer 25

Neutralization (prevention of microbial activity via direct binding, Fc independent)
Opsonization (tagging microbes for phagocytosis. Eg. IgG Fc binding to CD64 on neutrophil, macrophage, leading to degradation )
Antibody Dependent Cellular Cytotoxicity: (IgG Fc activates NK cell via CD16 , leading to degranulation)
Complement (IgM and IgG recruit complement MAC system).

Question 26

2 types of antibody production

Answer 26

T cell independent: Recognition of antigen by antibody attached to B cell. Signal 2 = PAMP via TLR on B cell. Leads to short lived response of mostly IgM (pentameric).
T cell dependent: Also antibody binding to antigen. Endocytosis of pathogen by B cell, presentation on MHC II, binding by helper T cell. Promotion of CD40 receptor on B cell, binding to CD40 ligand on T cell. B cell receives adtl. cytokines, which gives this signals 2+3. Leads to affinity maturation, isotype switching (IgG, etc.) and long lived memory.