Quiz Flashcards
all penicillins (beta lactams) are bacteriostatic/bacteriocidal?
bacteriocidal
which antibiotic can cause photosensitivity?
doxycycline
which antibiotic can worsen epileptic control?
all quinolones (…floxacin)
which drug is not adequate for strep pneumonia
- doxycycline
- clarithromycin
- co amoxiclav
- ciprofloxacin
- amoxicillin
ciprofloxacin
why is clarithromycin sometimes added in pneumonia management?
atypical organisms cover
what is the respiratory quinolone?
levofloxacin
which drug is not absorbed systemically when taken orally?
- clindamycin
- clarithromycin
- vancomycin
- ciprofloxacin
- aztreonam
vancomycin
describe C diff
anaerobic
spore forming
can C diff be carried asymptomatically?
yes
antimicrobials can disrupt the normal human micro flora for how long?
> 6 months
why is amoxicillin not used in UIT?
doesn’t cover pathogens (many E. coli are resistant)
what commonly causes UTI?
E. coli
does amoxicillin treat enterococcus?
yes
name side effects of quinolones
C. Diff (stop immediately if diarrhoea occurs)
diffuse tendinitis
psychiatric side effects
AAA rupture
oral bioavailability of quinolones?
very good
almost as good as IV
what does clindamycin not cover?
gram -ves (e.g proteus)
name an antibiotic which is only used as an IV preparation
gentamicin (however can be used as drops in the ear)
aztreonam
describe salmonella enteritidis?
gram -ve
name a gram +ve bacillus
listeria
campylobacter, salmonella and shigella are all what gram stain?
-ve
2 risks of co-amoxiclav?
cholestatic jaundice (liver disease) C. Diff
what 3 things are raised in sepsis?
IL 6
CRP
WCC
how does sepsis affect platelet count?
reduced
name 3 conditions associated with AIDS
recurrent pneumonia
oropharyngeal candida
salmonella bacteraemia (also seen in sickle cell)
antibiotic used in gram -ve cover of an ESBL producing klebsiella?
meropenem
ESBL producing bacteria are resistant to most of what class of antibiotic?
beta lactamase
vancomycin is ineffective against what?
gram -ves
list 3 organisms on Duke’s criteria
kingella kingae (HACEK)
bartonella
enterococcus faecalis
how does rifampicin affect warfarin?
reduces effect
who should tetracyclines be avoided in?
<12 yrs old
what is the most common cause of cellulitis?
skin commensals
does enterococcus faecium have a vaccine?
no
does whooping cough have a vaccine?
yes
what is typically known as “walking pneumonia” as it often has a severe X ray but hardly any symptoms?
mycoplasma
which antibiotic should be avoided as monotherapy?
rifampicin
which spread through sneezing
- pneumococcus
- legionella
- measles
- pneumocystis pneumonia
measles
how often must blood cultures be repeated if MSSA is found?
2-3 days
MRSA can colonise where?
nose