Quiz Flashcards

1
Q

all penicillins (beta lactams) are bacteriostatic/bacteriocidal?

A

bacteriocidal

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2
Q

which antibiotic can cause photosensitivity?

A

doxycycline

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3
Q

which antibiotic can worsen epileptic control?

A

all quinolones (…floxacin)

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4
Q

which drug is not adequate for strep pneumonia

  • doxycycline
  • clarithromycin
  • co amoxiclav
  • ciprofloxacin
  • amoxicillin
A

ciprofloxacin

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5
Q

why is clarithromycin sometimes added in pneumonia management?

A

atypical organisms cover

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6
Q

what is the respiratory quinolone?

A

levofloxacin

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7
Q

which drug is not absorbed systemically when taken orally?

  • clindamycin
  • clarithromycin
  • vancomycin
  • ciprofloxacin
  • aztreonam
A

vancomycin

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8
Q

describe C diff

A

anaerobic

spore forming

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9
Q

can C diff be carried asymptomatically?

A

yes

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10
Q

antimicrobials can disrupt the normal human micro flora for how long?

A

> 6 months

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11
Q

why is amoxicillin not used in UIT?

A

doesn’t cover pathogens (many E. coli are resistant)

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12
Q

what commonly causes UTI?

A

E. coli

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13
Q

does amoxicillin treat enterococcus?

A

yes

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14
Q

name side effects of quinolones

A

C. Diff (stop immediately if diarrhoea occurs)
diffuse tendinitis
psychiatric side effects
AAA rupture

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15
Q

oral bioavailability of quinolones?

A

very good

almost as good as IV

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16
Q

what does clindamycin not cover?

A

gram -ves (e.g proteus)

17
Q

name an antibiotic which is only used as an IV preparation

A

gentamicin (however can be used as drops in the ear)

aztreonam

18
Q

describe salmonella enteritidis?

A

gram -ve

19
Q

name a gram +ve bacillus

A

listeria

20
Q

campylobacter, salmonella and shigella are all what gram stain?

A

-ve

21
Q

2 risks of co-amoxiclav?

A
cholestatic jaundice (liver disease)
C. Diff
22
Q

what 3 things are raised in sepsis?

A

IL 6
CRP
WCC

23
Q

how does sepsis affect platelet count?

A

reduced

24
Q

name 3 conditions associated with AIDS

A

recurrent pneumonia
oropharyngeal candida
salmonella bacteraemia (also seen in sickle cell)

25
Q

antibiotic used in gram -ve cover of an ESBL producing klebsiella?

A

meropenem

26
Q

ESBL producing bacteria are resistant to most of what class of antibiotic?

A

beta lactamase

27
Q

vancomycin is ineffective against what?

A

gram -ves

28
Q

list 3 organisms on Duke’s criteria

A

kingella kingae (HACEK)
bartonella
enterococcus faecalis

29
Q

how does rifampicin affect warfarin?

A

reduces effect

30
Q

who should tetracyclines be avoided in?

A

<12 yrs old

31
Q

what is the most common cause of cellulitis?

A

skin commensals

32
Q

does enterococcus faecium have a vaccine?

A

no

33
Q

does whooping cough have a vaccine?

A

yes

34
Q

what is typically known as “walking pneumonia” as it often has a severe X ray but hardly any symptoms?

A

mycoplasma

35
Q

which antibiotic should be avoided as monotherapy?

A

rifampicin

36
Q

which spread through sneezing

  • pneumococcus
  • legionella
  • measles
  • pneumocystis pneumonia
A

measles

37
Q

how often must blood cultures be repeated if MSSA is found?

A

2-3 days

38
Q

MRSA can colonise where?

A

nose