Choosing an Antibiotic Flashcards
how do the 4 C antibiotics cause C. Diff?
very broad spectrum so alter gut flora allowing C. Diff to proliferate
drawbacks of broad spectrum antibiotics?
increase rate of bacterial mutation
causes increase in resistant bacteria and proliferation of C. Diff
2 general rules for antibiotic prescribing?
shorter duration and higher dose (less time for bacteria to mutate)
switch from IV to oral as quick as possible
what type of bacteria generally causes abscesses?
anaerobes
give a feature of atypical bacteria, where do they usually occur?
no cell wall
usually in resp tract
name 5 risks which accompany all antibiotics
nausea vomiting diarrhoea rash candida
what 2 antibiotics can cause cholestatic jaundice?
flucloxacillin
co-amoxiclav
side effect of vancomycin?
red man sydrome
which group of antibiotics causes GI disturbance?
macrolides (clarithromycin, azithromycin etc)
name 6 side effects of quinolones
C. Diff AAA rupture Tendinitis psychiatric long QT interval convulsions
name 3 side effects of tetracyclines
photosensitivity
teeth staining
hepato-toxicity
which antibiotic can cause steven Johnson syndrome?
co-trimoxazole
what is steven Johnson syndrome?
disorder of skin and mucosa (usually reaction to medication)
begins as flu-like symptoms
then progresses to rash which spreads becomes red/purpuric and blisters
most antibiotics have what effect of other drugs?
usually inhibit
where is pseudomonas usually found in the environment and where does it usually occur in the body?
found in soil
usually occurs in resp tract
