Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cardiac and Respiratory Physiology > Quiz 6 > Flashcards

Quiz 6 Flashcards

1
Q

what is PaO2 of fetus

A

20-30 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

3 fetal adaptations to hypoxia

A
  1. specialized circulation
  2. Increased blood affinity for oxygen (fetal hemoglobin)
  3. Increased [Hgb] and combined cardiac output
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

is oxyhemoglobin saturation higher or lower in the fetus than the adult

A

lower by 25%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Is oxygen content of the mother higher or lower than fetus

A

similar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ductus arteriosus moves blood that got into the _____ to the _____

A

right ventricle and pulmonary artery to the aorta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

relationship between placental blood flow and pulmonary blood flow

A

inverse

as pulmonary flow goes down, placental flow goes up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

hemodynamics in fetus is largely influenced by

A

high pulmonary vascular resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Is the placenta more or less efficient than the lung at gas exchange

A

less

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what 3 things make the placenta more/less efficient than the lung

A
  1. 10 to 20% more O2 exchanged per unit weight in the lung
  2. placenta consumes 50% of available oxygen
  3. 20-35% of available blood flow functionally bypasses gas exchange sites
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

5 factors that affect placental gas exchagne

A
  1. area
  2. blood flow to the maternal side of the placenta
  3. fetal blood flow (relatively high CVO)
  4. Oxygen content of maternal blood
  5. Reltaive affinities of fetal and maternal hemoglobin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Fetal Hgb is present at what week of gestation

A

12 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

fetal hgb makes up what % of total hgb

A

75-85

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

p50 for fetal hemoglobin is higher or lower than maternal

A

lower

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

why does fetal hemoglobin bind oxygen more tightly than maternal/adult hemoglobin

A

doesn’t bind 2, 3 DPG as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is implication of steeper curve for fetal hemoglobin

A

allows release of oxygen w/ small changes in PaO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

describe double Bohr effect

A
  • on maternal side, the CO2 causes the O2 disassociation curve to shift to the right
  • on the fetal side, the release of CO2 causes the disassociation curve to shift to the left
17
Q

double Bohr effect accounts for what % of O2 exchange

A

8

18
Q

double haldane effect accounts for what % of CO2 exchange?

A

46%

19
Q

Which part of GI is developed during first 16 weeks of gestation

A

conducting/airways and arterioles

20
Q

does vascular muscle thickness of lungs increase/decrease during late development and what is the implication of this?

A

decrease–this decreases PVR

21
Q

main contributor to PVR

A

low O2, high pH

22
Q

t/f fetal lung fluid is derived from amniotic fluid

A

f–made in lungs

23
Q

what 2 things are essential for lung growth?

A

maintenance of lung volume and fetal breathing

24
Q

3 groups of changes that take place during the transition from fetal to neonatal life

A

changes in circulation
establishment of air breathing
surfactant

25
Q

What are the two contributing factors to decrease PVR at birth

A

stretch and O2

26
Q

What two factors allows ductus arteriosus to close

A 
oxygenation
decrease PGE (prostaglandins)
27
Q

which shunt closes the fastest, slowest

A

ductus venosus

foramen ovale

28
Q

3 main stimuli for first breath?

A

temperature drop
gravity
stress–chatecholines

29
Q

What makes breathing continuous

A

reduction in inhibition

30
Q

3 things that remove fetal lung fluid

A
  1. labor
  2. delivery
  3. circulation and lymphatics
31
Q

3 ways babies maintain FRC

A

Expiratory braking maneuver
crying
grunting

32
Q

t/f newborns breakdown their surfactant

A

f

33
Q

mutations in SP-B gene cause what

A

fatal

34
Q

mutations in SP-C gene cause what

A

variable and severe interstitial lung disease in infants

35
Q

components of surfactnat appear in amniotic fluid when

A

34-36 weeks gestation

36
Q

4 mechanical disadvantages of the neonatal chest/lung

A
  1. more circuluar –less bucket handle
  2. diaphragm is less domed/more flattened
  3. High compliance
  4. disadvantage is accentuated when supine

Cardiac and Respiratory Physiology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions