QUIZ

Question 1

The key components of PMED are?

Answer 1

Individualised health strategies biochemistry, genome, lifestyle

Use of clinical and molecular measurments of the individual

Question 2

Pharmacogenomics is:

Answer 2

the interaction between drugs and the genome

Question 3

What are the key drivers in the emergence of personalised medicine?

Answer 3

The demise of the block buster drug isn’t occurring in a vacuum but is influenced by many different factors, it can be argued that it is driving pharma to reconsider what they have on their shelves encouraging repurposing. Personalised medicine is a big global market but the drugs use in individual cases is relatively small in market value compared to the traditional value of block busters

Question 4

Drug repurposing is

Answer 4

Drug repurposing doesn’t involve redesigning or modify drugs. It is very much about finding new uses for old drugs which may have been shelved for all sorts of reason

Question 5

which phase of clinical trial is primarily concerned with drug safety

Answer 5

phase 1

Question 6

incidental findings are?

Answer 6

findings that are the result of a clinical investigation that were not the origianl aim of the investigation

Question 7

sanger seq method for sequencing DNA that uses a fluorescent dye terminator to randomly terminate elongation. These molecules:

Answer 7

have a 3’ hydroxyl group missing from the carbon ring of the sugar

Question 8

sanger seq uses an isothermal reaction which includes

Answer 8

strand sepertion
annealing a primer
extension
termination

Question 9

sanger seq is a method that seperates a pop of moleculrs produced from an amplified seq using

Answer 9

capillary electrophoresis