quiz 5 GI constipation meds

Question 1

first line tx
bulk forming 3
softener
osmotic laxative 3

Answer 1

bulk forming hydrophillic colloids
-psyllium
-methylcellulose
-polycarbophil
stool softeners (docusate)
Osmotic laxatives
-lactulose 
-sorbitol 
-magnesium salts (avoid if renal insufficiency)

Question 2

2nd line
stimulants (2)
lubricants 1
suppository 4

Answer 2

stimulants
-senna/docusate
-bisacodyl
Lubricants -mineral oil
suppositories
-osmotic:sodium phosphate
-lubricant:glycerine
-stimulant: bisacodyl
-enema:fleet (saline)

Question 3

2nd line meds

Answer 3

lubiprostone
prucalopride (^SI)
Guanylate cyclase agonists (adults)
-linaclotide
-plecanatide

Question 4

peripheral acting opioid receptor antagonist (OIC)

Answer 4

methylnaltrexone
naloxegol
naldemedine