Quiz 4. Hose Defense Mechanisms in Oral Cavity Flashcards
If there’s enough bacteria what happens?
Infection
Profileration
Multiplication of bacteria
The Mouth is the beginning of infection
Gateway to GI
Has many defense systems
Defense systems
Anatomic Barriers
Normal Oral Flora
Immune Systems
Saliva
Anatomic Barriers
Epithelium (keratinized) and an ideal dentition
Can’t cause infection w/o getting past this barrier
Normal Oral Flora
Bacteria that discourage colonization
Immune System
Cellular and humoral components
Saliva
Contains immunoglobins
What lacks keratin and is susceptible for invasion?
Junctional epithelium (where perio pocket is)
Which epithelium is highly vascularized?
Mucosal
What are anatomic situations that give pathogens an advantage to colonize?
Restorations w/ overhangs, lack of interdental papillae, perio pockets, drifting or crowded teeth
Pyogenic graulomas
Associated with prego women
Not associated with bone loss
Tooth enamel is constantly
undergoing a process of demineralization and remineralization
Demineralization is reversible
Saliva
Flouride (Inhibits demineralization, systemic, topic, restorations)
What’s in normal oral flora?
Saliva pH
Water content in saliva
Saliva as a buffer
Lymph portion of Oral Cavity
Cellular (T-cells from Thymus)
Humoral (B-cells from Bone Marrow)
Both parts of lymph system are involved in defending the body
Candida Albicans
Yeast organism
Kept in check by saliva, oral flora, a T-cells
If get past any of these it can cause an infection
What is prevalent in acute inflammation?
Neutrophil
Blood in the Immune System
Granulocytes find and attack foreign invaders
Saliva in promoting homeostasis
Salivary flow functions continuously
@ Sleep- lowest
@ Food ingestion- greatest
What does the Parotid gland secrete?
Sodium Bicarbonate
Sialorrhea
High saliva flow
Sialoliths
Saliva stones
Sjogren’s Syndrome
Autoimmune associated w/ other autoimmune diseases
All membranes in body are drier
Organic Components of Saliva
Salivary proteins
What do salivary proteins do?
Control status of Ca and P in saliva
Prevent rapid drop in pH
What do salivary mucins do?
Help clear carbs from mouth and protect against caries
Help swallow food
Regulate enzymes that are responsible for tissue repair
Immunoglobulins
Antibodies made of protein
Defend body against all types of infection even when there is none (ex: allergic reaction)
IgM
Largest, earliest to appear
Found in blood
Can’t exit in circulatory system
IgG
Most abundant for food allergies
IgD
Smallest concentrations linked to IgM
IgE
Widespread throughout the body
Found in blood, defense against parasitic infections (fights cancer cells)
IgA
Initiates inflammatory process and prevents both bacteria and viruses from adhering to mucous membranes
Found in tears and saliva
Most important to dentristy
