quiz 3 Flashcards
Sharp localized pain fibers?
A delta
dull pain fibers?
C fibers
what neurotransmitters are released from the dorsal horn?
Substance P
Glutamine
Calcitonin related peptides
how long is definition of chronic pain?
> 3 months or longer than normal tissue healing
which receptor effects urinary symptoms?
Kappa
how does morphine affect the receptor?
mu agonist in inhibitory way
inhibits ATP to cAMP
which of the opiates are natural?
Morphine
what in the structure of morphine give its effects?
S. Antiomer
what type of pain does morphine relieve the best?
continuous dull pain
who is at higher risk of morphine related respiratory side effects?
women
what does glucagon do to counteract morphine?
increases cAMP
good choice drug for renal failure?
dilaudid (no active metabolites)
how does fentanyl differ from morphine?
no histamine release or active metabolite
potency of fentanyls from least to most
Alfentanyl < fentanyl < sufentanyl < remifentanyl
whats the issue with sufentanyl
longer duration of action -> higher risk of accumulation