quiz 3 Flashcards

1
Q

Sharp localized pain fibers?

A

A delta

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2
Q

dull pain fibers?

A

C fibers

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3
Q

what neurotransmitters are released from the dorsal horn?

A

Substance P
Glutamine
Calcitonin related peptides

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4
Q

how long is definition of chronic pain?

A

> 3 months or longer than normal tissue healing

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5
Q

which receptor effects urinary symptoms?

A

Kappa

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6
Q

how does morphine affect the receptor?

A

mu agonist in inhibitory way

inhibits ATP to cAMP

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7
Q

which of the opiates are natural?

A

Morphine

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8
Q

what in the structure of morphine give its effects?

A

S. Antiomer

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9
Q

what type of pain does morphine relieve the best?

A

continuous dull pain

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10
Q

who is at higher risk of morphine related respiratory side effects?

A

women

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11
Q

what does glucagon do to counteract morphine?

A

increases cAMP

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12
Q

good choice drug for renal failure?

A

dilaudid (no active metabolites)

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13
Q

how does fentanyl differ from morphine?

A

no histamine release or active metabolite

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14
Q

potency of fentanyls from least to most

A

Alfentanyl < fentanyl < sufentanyl < remifentanyl

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15
Q

whats the issue with sufentanyl

A

longer duration of action -> higher risk of accumulation

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16
Q

The “fentanyls” half lifes shortest to longest

A

Alfentanyl < sufentanyl < fentanyl

17
Q

important for sufentanyl?

A

need normal kidney function

18
Q

“fentanyls” with quickest onset?

A

Alfentanyl

Remifentanyl

19
Q

important for alfentanyl?

A

normal liver function

20
Q

what is remifentanyl good for

A

quick on and off for neuro cases