Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology III > Quiz 2 Reverse > Flashcards

Quiz 2 Reverse Flashcards

1
Q

1 - latent in trigeminal ganglia2 - latent in sacral ganglia

A

Which sites do HSV 1 & 2 prefer?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
  1. Acyclovir - Zovirax- oral, topical, IV2. Valacyclovir - Valtrex - only oralProdrugs - prevent viral shedding
A

What are the meds for herpes & how do they work & drug forms?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

RotavirusFecal-oral transmission

A

What is the MCC of severe diarrhea in children?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3 dose regimen to infants 6-32 wksSelf limiting - rehydration

A

Who gets the rotavirus vaccine & how do you treat when you get it?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RNA Readily inactivated w/ soap, water & disinfectantsMCC of bronchiolitis & PNA in kids <1yr

A

What type of virus is RSV?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Palivizumab - Synagis Tx - Ribavirin aerosol

A

What is the vaccine & Tx for RSV?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
  1. Extracellular - w/in lung cavities2. Inside granulomas3. W/in macrophages
A

What are the 3 environments TB likes to be in?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Growth phase

A

What phase do TB drugs target?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

8 weeks of 1. Rifampin2. Isoniazid3. Pyrazinamide4. EthambutolFollowed by 16 wks of:1. Rifampin2. Isoniazid

A

What is typical therapy for TB?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pregnant ladies - yesKids - don’t use Ethambutol <5y/o

A

Can you use TB therapy in pregnant ladies & kids?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hepatotoxicity!!!

A

What is the most common side effect of all TB drugs?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

For TBinterferes w/ mycolic acid (cell wall)

A

How does isoniazid work?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Slow - drug levels rise & may cause peripheral neuropathyFast - Make more metabolite & may cause hepatotoxicity

A

What is the problem w/ slow/fast acetylators & isoniazid?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

2C19 & 2D6Careful w/ MAOIs

A

What drug interactions should you consider with isoniazid?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Rifampin - TB TxBactericidal Used in active TBAlso urine & breast milk

A

What drugs cause your tears to turn red?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Active TB TxInhibits cell wall synthesisBacteriostatic

A

How does ethambutol work?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Active TB TxEffects ATP - disrupts plasma membrane & energy metabolism Bactericidal

A

How does pyrazinamide work?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q
  1. Optic neuritis - dec. acuity, scotoma, color blindness, visual defects 2. Hepatotoxicity3. GI
A

ADRs ethambutol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q
  1. Hyperuricemia2. Hepatotoxicity3. Loss of glycemic control4. GI
A

ADRs pyrazinamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Aminoglycoside abxInterrupts formation of proteins Injectable only

A

How does streptomycin work?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

CN VIII1. Nephrotoxicity2. Neurotoxicity3. HOTN4. Ototoxicity - auditory & vestibular

A

ADRs streptomycin

22
Q
  1. Chloroquine For active & prophylactic malaria
A

What are the 4-aminoquinolones & when are they used?

23
Q

For active & prophylactic malaria1. Mefloquine Works in blood stage CV changes & seizure inc, CNS

A

What are the 4-methanoloquinolines & ADRs?

24
Q
  1. Primaquine For active & prophylactic malariaCareful w/ G6PD deficiency
A

What are the 8-aminoquinolines?

25
Q
  1. Atovaquone/Proguanil (Malarone)For active & prophylactic malariaCareful in AIDS Pts (NNRTIs, PIs)
A

What are the anti-folates for malaria?

26
Q
  1. Doxycylcine2. Tetracycline3. ClindamycinActs on shizonts - delay death mechanismOnly used in combo therapy
A

What are the antimicrobials for malaria?

27
Q
  1. Artemether (Coartem)Short 1/2 lifeDO NOT use as monotherapy!For active malaria
A

What are the artemisinin derivatives?

28
Q
  1. Tinidazole (Tindamax)2. Iodoquinol (Yodoxin)3. Paromomycin 4. Metronidazole (Flagyl)
A

What drugs would you use for a protozoal infection?

29
Q
  1. C. Diff2. Amebiasis3. Giardiasis4. Trich5. Anaerobic infections DO NOT drink!
A

What can you treat w/ Metronidazole?

30
Q

We have Type II immunity

A

Why are helminth infections worse in kids?

31
Q

Ascaris wormies

A

What is the MC infestation throughout the world?

32
Q
  1. Benzimidazoles2. Ivermectin3. Praziquantel4. Pyrantel pamoate
A

What classes of drugs would you use for a helminth infection?

33
Q

Type of Benzimidazole for helminth1. Bone marrow suppression2. Inc. liver transaminases3. HA4. Inc. ICP5. Dizziness, vertigo6. Ab pain, N/V

A

ADRs Albendazole

34
Q

For Helminth - aka Stromectol P-glycoprotein activity can reduce ivermectin levels in CNSRARE - reactions prob due to wormie dying 1. Pruritis, fever, LN tenderness 2. Tachycardia3. Eosinophilia, leukocytes dec., Hgb inc. Get routine blood work!

A

ADRs Ivermectin

35
Q

Major substrate of CYP3A4Aka BiltricideRifampin dec. Praziquantel levels

A

How is Praziquantel metabolized?

36
Q

Pyrantel Pamoate aka Pin-XPoor oral absorption GI problemsCareful if hepatic impairment

A

How do you Tx pinworms?

37
Q
  1. Triazole - Fluconazole2. Imidazole - Ketoconazole
A

What are the azole antifungals?

38
Q
  1. Kidney & liver function2. Electrolytes3. Vital signs 4 hrs post infusion
A

What do you need to monitor when using Amphotericin B?

39
Q
  1. Acetaminophen2. CorticosteroidAlso give K supplementation w/ prolonged therapy, load w/ NaCl injection
A

What do you give with amphotericin B to prevent some of the side effects?

40
Q
  1. Fever & chills2. Tachypnea, stridor3. Nephrotoxicity4. Anemia
A

ADRs amphotericin B

41
Q

Micafungin - Mycamine

A

What are the echinocandins?

42
Q
  1. Nasal corticosteroids2. Singulair3. Ipratropium nasal spray4. Cromolyn nasal spray5. Antihistamines
A

What are the meds for allergic rhinitis?

43
Q

Fluticasone nasal - Flonase Need 1-2 wks of therapy until max efect

A

What are the corticosteroids for allergic rhinitis?

44
Q
  1. Singulair - Montelukast Improves rhinorrhea, sneezing & congestoin
A

What the the leukotriene modifiers for allergic rhinitis?

45
Q
  1. Cromolyn nasal - NasalCromReduce release of histamine from mast cells Can work w/in 30 min
A

What are the mast cell stabilizers for allergic rhinitis?

46
Q
  1. Ipratropium nasal - Atrovent Blocks parasympathetic nerve effect - Vidian nerve is postganglionic parasympathetic Can cause xerostomia & taste perversion Tx of rhinorrhea
A

What are the anticholinergics for allergic rhinitis?

47
Q
  1. Claritin - Loratadine
A

What are the antihistamines for cold?

48
Q

Pseudoephedrine - Sudafed 1. CV2. Metabolic3. CNS4. Endocrine

A

What are the decongestants for cold & ADRs?

49
Q
  1. Dextromethorphan - DelSymDepression of medullary cough center - sigma receptor stimulation 2. Benzonanatate Intractable cough Tx
A

What are the antitussives for cold?

50
Q

<4 y/o

A

At what age should children NOT receive OTC cold & cough meds?

Pharmacology III (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions