Quiz 2: Diagnostic, Interventional, and Treatment Procedures Flashcards

1
Q

what is the first step in the fight against breast cancer

A

detection

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2
Q

the microscopic examination of cell samples

A

cytological analysis

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3
Q

the microscopic examination of tissue samples

A

histological analysis

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4
Q

the removal of the content of a cyst for testing of analysis

A

fine needle aspiration (FNA)

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5
Q

for a biopsy on a nonpalpable lesion, how would you determine its exact location

A

stereotactic imaging

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6
Q

what is done to triangulate a lesion for a stereotactic biopsy?

A

the tube is angled 15° to the left & right of the x axis for 2 scout images.

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7
Q

are used to position a biopsy probe within the breast at the calculated coordinates

A

stereotactic calibrations

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8
Q

what are the 2 machine options for stereotactic breast biopsies?

A

add on attachment to regular mammogram machine or

a dedicated prone biopsy system

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9
Q

what is done when stereotactic breast biopsy is not available?

A

preoperative needle localization

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10
Q

how much guide wire is left in the lesion after a preoperative needle localization?

A

5 mm

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11
Q

the taking of a sample specimen for cytological or histological analysis

A

breast biopsy

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12
Q

is used to obtain cellular material from the area in question for cytological analysis

A

fine needle biopsy

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13
Q

can be used to diagnose both cystic and solid lesions, such as fibroadenomas

A

fine needle biopsy (FNB)

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14
Q

the most commonly performed, minimally invasive technique

A

core biopsy

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15
Q

removes a sample of tissue, unlike FNB

A

core biopsy

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16
Q

what gauge needle is used during core biopsies?

A

11-14 gauge or larger

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17
Q

which 2 types of biopsies involve cutting the skin by <1/4”?

A

Automatic or Mechanical Core “Gun”

Vacuum Core Biopsy

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18
Q

a hollow probe is inserted and guided to the area of interest. A cylinder of tissue is then suctioned out and pulled through a hole in its side. a rotating knife inside the probe cuts the tissue sample from the rest of the breast

A

Vacuum Core Biopsy

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19
Q

is used to remove parts of a lesion

A

incisional biopsy

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20
Q

is used to remove the entire lesion

A

excisional biopsy

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21
Q

which type of biopsy has the lowest false negative rates?

A

open surgical biopsy

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22
Q

which surgery is the most invasive and has the highest complication rate?

A

open surgical biopsy

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23
Q

what false negative rate has been reported for core biopsies?

A

4%-10%

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24
Q

what is the false negative rate for FNB’s?

A

5%-20%

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25
Q

what are the surgical clips made of that are placed at the biopsy site of the breast?

A

stainless steel or collagen based products

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26
Q

true or false: a specimen radiograph should be performed after every biopsy to confirm that the lesion was removed and that the margins are clean

A

true

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27
Q

t/f: technologists should always use compression and magnification when radiographing biopsy specimens

A

true

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28
Q

can be performed to evaluate suspicious nipple discharge

A

ductography

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29
Q

The general term used when describing reshaping of the breast

A

Mammoplasty

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30
Q

Includes any reconstruction of the breast for nonmedical reasons

A

Cosmetic intervention

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31
Q

What is it called when an implant is placed in front of the pectoral muscle?

A

Subglandular or retromammary implants

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32
Q

What is it called when an implant is placed behind the pectoral muscle?

A

Subpectoral or retropectoral implants

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33
Q

The surgical removal of the entire breast

A

Mastectomy

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34
Q

Involves the removal of the entire breast, lymph nodes, in the chest wall muscles under the breast

A

Radical mastectomy

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35
Q

Is rarely performed today because the modified mastectomy is just as effective and is less debilitating and deforming

A

Radical mastectomy

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36
Q

Involves the removal of the entire breast, including the nipple/areola region and some of the under arm lymph nodes

A

Modified radical mastectomy

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37
Q

Involves the removal of the breast tissue, but the nipple-areola complex remains.

A

Nipple-sparing mastectomy

38
Q

This procedure can be used by women with relatively small tumors or non-aggressive cancers or as a prophylactic procedure

A

Nipple – sparing mastectomy

39
Q

Involves the removal of a healthy breast when the individual has a high risk factor for developing breast cancer

A

Prophylactic mastectomy

40
Q

Involves the removal of the malignant tumor in the margins of the surrounding normal breast tissue

A

Lumpectomy

41
Q

Is often combined with other therapy options, such as radiation treatment, chemotherapy, or hormonal treatment.

A

Lumpectomy

42
Q

How many weeks of radiation therapy is usually given if a lumpectomy is followed by radiation therapy?

A

6 weeks

43
Q

How long does it usually take to begin radiation treatment after surgery?

A

1 month (to allow for healing)

44
Q

What two options can be given to control the systemic spread of breast cancer after a lumpectomy?

A

Chemo therapy or treatment with the drug tamoxifen

45
Q

Clear fluid trapped in the wound

A

Seroma

46
Q

This procedure to remove the under arm lymph nodes during mastectomy or lumpectomy

A

Axillary node dissection

47
Q

Involves the removal of only one to three sentinel lymph nodes in the axillary area

A

Sentinel lymph node biopsy

48
Q

What is taken into consideration when staging breast cancer?

A

Invasive or non-invasive, determine size and location, determines whether there is lymph node involvement, and determines whether the cancer has spread to other parts of the body

49
Q

During the American joint committee on Cancer staging system, what does the TN & M stand for?

A

Tumor size, lymph node spread, assess distant metastasis

50
Q

Usually begins one month after surgery, giving the breast time to heal. Treatment time is typically 15 to 30 minutes with radiation given five times per week for 5 to 8 weeks

A

External beam radiation

51
Q

Involves applying radiation from inside out. Treatment can be reduced from eight weeks to 5-9 days

A

Internal beam radiation

52
Q

What is another name for internal beam radiation?

A

Brachytherapy

53
Q

How soon can internal beam radiation therapy begin after a lumpectomy?

A

Immediately

54
Q

Is an adjuvant therapy and involves the use of drugs to treat cancer that may have spread beyond the breast

A

Chemotherapy

55
Q

Is given before surgery to help shrink the cancerous tumor

A

Neoadjuvant chemotherapy

56
Q

Is given in addition to another breast cancer treatment, for example, mastectomy

A

Adjuvant chemotherapy

57
Q

How long does chemotherapy treatment last?

A

3-6 months

58
Q

Will determine the exact genetic profile of the altered cancer cells & design a treatment plan based on the nature of these cells or subcells

A

Molecular treatment

59
Q

What drug class is often used during molecular treatment?

A

SERMs (selective estrogen receptor modulators)

60
Q

Are used to shrink or stop the recurrence of breast cancer or lower the risks of breast cancer recurrence in postmenopausal women

A

Selective Estrogen Receptor Modulators (SERMs)

61
Q

what are the 3 drug options for molecular treatment?

A

tamoxifen, raloxifene (Evista), and Fulvestrant (Faslodex)

62
Q

which SERM has fewer adverse effects?

A

Raloxifene (Evista)

63
Q

which SERM is antiestrogen?

A

Fulvestrant (Faslodex)

64
Q

slows or stops the growth of hormone-sensitive tumors by blocking the body’s ability to produce hormones or by interfering with hormone action.

A

hormone therapy

65
Q

what is used to treat tumors if they are hormone insensitive?

A

aromatase inhibitors

66
Q

used to treat estrogen-receptor-positive (ER+) cancers

A

aromatase inhibitors

67
Q

can be used to block the activity of an enzyme called aromatase

A

aromatase inhibitors

68
Q

the body uses this enzyme to make estrogen in the ovaries and other tissues

A

aromatase

69
Q

are used primarily in postmenopausal women because the ovaries in premenopausal women produce too much aromatose

A

aromatase inhibitors

70
Q

what are the 3 drugs used for aromatase inhibitation?

A

exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara)

71
Q

effective therapy for HER2/neu aggressive cancers

A

Trastuzumab (Herceptin)

72
Q

what is a major adverse effect of trastuzumab?

A

damage to the heart muscle

73
Q

effective in the treatment of HER2 aggressive cancers and cancers that are both HER2+ and ER+

A

Lapatinib (Tykerb)

74
Q

major side effect of this drug causes liver damage

A

Lapatinib (Tykerb)

75
Q

can show inherited mutations that predispose a woman to cancer

A

Gene Therapy

76
Q

what are 3 uses of gene therapy?

A
  1. inserts specific genes into cells to restore missing function or give new function
  2. prevents cancer from developing
  3. stops other genes that allow cancer cells to metastasize
77
Q

seeks to create an immune system response within each patient and to prime the body to kill cancer cells or to strengthen the immune systems ability to recognize and attack cancer cells

A

immunotherapy or biotherapy

78
Q

what percent of cancer patients experience pain?

A

30%

79
Q

what percent of patients are undertreated for cancer pain

A

50%

80
Q

what are the 2 types of breast reconstruction done after breast cancer reconstruction?

A

immediate reconstruction and delayed reconstruction

81
Q

why may it be necessary to do a delayed reconstruction after post-breast cancer breast reconstruction?

A

if radiation immediately follows a mastectomy or if the skin is damaged by the radiation

82
Q

what are the modern techniques for breast implants?

A

behind the pectoral muscle (subpectoral or retropectoral)

83
Q

what are the older techniques for breast implants?

A

in front of the pectoral muscle (subglandular or retromammory placement)

84
Q

flap surgery that removes skin and fat from the abdomen, back, or buttocks and uses it to form a new breast

A

autologous tissue

85
Q

what does TRAM flap stand for?

A

transverse rectus abdominis myocutaneous flap

86
Q

when muscle, fat, and skin from abdomen is used to create a new breast mound

A

TRAM flap

87
Q

further surgery needed to make the nipple and areola after reconstruction

A

TRAM flap

88
Q

the flap is completely removed, and microsurgery is needed to recreate blood supply when the flap is positioned as a breast mold

A

free flap

89
Q

the flap remains attached to its original blood supply, and it is tunneled under skin to the breast area

A

pedicle flap

90
Q

what are the 3 autologous tissue ariations?

A

DIEP (deep inferior epigastric perforator), SIEP (superficial inferior epigastric perforator), latissimus flap

91
Q

what is the recovery time for most flap reconstruction?

A

4-6 weeks

92
Q

for flap reconstruction, how long are patients usually required to have a drain for?

A

1-2 weeks