Quiz 2

Question 1

Subcutaneous inject

Answer 1

under skin, vaccines

Question 2

IM

Answer 2

muscle (used for morphine)

Question 3

IP

Answer 3

peritoneal cavity (used for all other laps, caffeine is unknown)

Question 4

Alcohol behavioral tests

Answer 4

open field maze
rotorod/beam
warm plate/temp.

Rats low body temp, worse coordination, high anxiety

Question 5

Anxiety and Anticipation

Answer 5

Open field maze

Question 6

Concentrations: 
Scopolamine
Caffeine
Ethanol
Morphine sulfate
Diazepam

Answer 6

S- 1 mg/kg 
C- 20mg/kg
E- 1g/kg, diluted by half distilled water
MS- 5mg/kg IM injection
D-2.5 mg/kg

Question 7

Why IM?

Answer 7

slow absorption rate, so safe for rats

Question 8

Why IP?

Answer 8

Gets there quickly, avoids 1st pass metabolism, quick onset time.

Question 9

Condition placed preference- morphine

Answer 9

vertical and horizontal slits
8 day training
Subcutaneous injection.
Group A was saline, Group B was both alternated 3mg in 0.3 saline morphine S. in one vs. the other

Question 10

Serotinin, unlike choline

Answer 10

influenced by food

Question 11

Light-dark box

Answer 11

Measures anxiety
More time in dark = more anxious
Anxiolytics (GABA/Diazepam lab)

Question 12

Elevated Plus Maze

Answer 12

Measure anxiety
More time in closed = more anxiety
Anxiolytics (Gaba/Diazepam)

Question 13

Gaba/anxiolytics

Answer 13

= lower anxiety

Question 14

Open field maze was used…

Answer 14

Stimulants=10 mins
Alcohol=5 mins
Diazepam = 3 mins

Activity- squares entered
anxiety- number of inner/outer squares

Question 15

Temperature

Answer 15

base of tail, infrared

alcohol, opiates

Stimulant: increase temp
Alcohol: lower temp
opiates: higher

Question 16

Rotorod/beam

Answer 16

Alcohol and opiates

worse coordination in both

Question 17

Warm plate

Answer 17

pain

alcohol and opiates

Question 18

If you have too many depressants, how do you die?

Answer 18

Respiratory failure

Question 19

Side effect opiates

Answer 19

constipation

Question 20

Rats used were

Answer 20

Long Evans rats

Question 21

What experiments were mixed?

Answer 21

Water maze, morphine

Question 22

What experiments were between?

Answer 22

Caffeine, Alcohol, Diazepham

Question 23

proper way to hold rat

Answer 23

base of tail, by scruff of neck, over the neck/shoulders holding from back

Question 24

Once pipettor is set correctly, no need to check again

Answer 24

false

Question 25

methods:

Answer 25

subjects, apparatus, procedure

Question 26

Pipetting solution

Answer 26

Bradford