Exam 1 Administration Routes Flashcards
Oral (PO)
Absorbed from GI tract
Rectal
Absorbed from Rectal
Intravenous (IV)
Absorbed from blood vein
Intramuscular (IM)
inject to muscles
Intraperitoneal (IP)
inject through abominal wall into peritoneal cavity by the organs
Subcutaneous (SC)
BELOW the skin
Inhalation
Absorbed through lungs
Topical
Mucous membranes
Sublingual
Drug under tongue
Intranasal
Absorbed by nasal mucous
Transdermal
through skin SURFACE
Epidural
Spinal injection through vertical cloumn outside DURA.
Gene therapy
apply DNA to target site
Intrathecal
Subarachnoid space
Intracerebral
delivery directly to brain
Stereotaxic cannulation
Buccal
Absorption by mouth
Subject to 1st pass
Oral (some rectal)
Bypass 1st pass
Intravenous, intramuscular, inhalation, intranasal, sublingual, Buccal, transdermal
Bypass BBB
Intrathecal, Epidural, Intracerebral
Intranasal
Rapid speed
Intravenous Intraperitoneal Inhalation Epidural Buccal Sublingal
Slow speed
Oral, Intramuscular, subcuaneous, transdermal
Fast –> Slow:
Rectal, oral, intramsucular, subcutaneous, intravenous, inhalaton, sublingual
Intravenous Inhalation Sublingual Intramuscular* Subcutaneous* Rectal (VARIES) Oral
Disadvantage: absorption variability
Oral
Intraperitoneal
Subcuaneous
Rectal
Disadvantage: Irritation
Intramsucular
Inhalation
Intranasal
Transdermal
Alimentary canal used by
Oral, sublingual, buccal, rectal
Animals
intraperitoneal, intracerebral
Self-administration
Oral, Topical, sublingual, buccal, intranasal, transdermal
Weak acid
Aspirin
Penicillin
Warfarin
Phenobarbital
Weak base
Codeine, morphine, cocaine, amohetamine, nicotine, caffeine
Anti emetic
Sublingual
Rectal
Nitroglycerin
Cure angina
Sublingual/IV
Get to heart quick
Insulin
Subcutaneous
Spinal anesthetic
Surgury
Intrathecal
Progestin
Contraception
Various
Nicotin (cigar)
Stimulant
Bucal
Thiopental
Anesthesia
Intravenous
Lipid soluble, rapid onset
Deploro vera
Steroids
iM
Lipid soluble, slow
Vaccines/antipsychotics
IM