Quiz 2 Flashcards
6-mercaptopurine
Antimetabolite - interferes with cell cycle
Alprenolol
Beta-1 selective antagonists
Bevacizumab (Avastin)
Monoclonal antibody … Anti VEGF
Vincristine
Microtubule Inhibitors-halts anaphase
Docetaxel
Microtubule Inhibitors -stuck in metaphase
Carbachol
Direct acting, agonist for ACh
Tetrahydrozoline
(aka visine) Alpha-1 agonists
Lomustine
Alkylating Agents
Phentolamine
Non-selective alpha antagonists
Edrophonium (Tensilon)
Short Indirect acting, inhibits AChE
Tiotropium (Spiriva)
Muscarinic blocker
Dicyclomine
Muscarinic blocker
Bethanechol
Direct acting, agonist for ACh
Parathion
Long indirect acting, inhibits AChE
5-fluorouracil
Antimetabolite - interferes with cell cycle
Tacrine
Intermediate Indirect acting, inhibits AChE
Labetalol
Non-selective beta antagonists with partial alpha-1 antagonist activity
Isoproterenol
Non-selective beta agonist
Betaxolol
Beta-1 selective antagonists
Nebivolol
Beta-1 selective antagonists
Rivastigmine
Intermediate Indirect acting, inhibits AChE
Atenolol
Beta-1 selective antagonists
Exemestane
Steroid Hormones and Antagonists ….. Aromatase inhibitor
Apraclonidine
Alpha-2 agonists
Methotrexate
Antimetabolite - interferes with cell cycle
Midodrine
Alpha-1 agonists
Cyclopentolate
Muscarinic blocker
Esmolol
Beta-1 selective antagonists
Carteolol
Non-selective beta antagonists with partial agonist effect
6-thioguanine
Antimetabolite - interferes with cell cycle
Bicalutamide
Steroid Hormones and Antagonists ….. Nonsteroidal antiandroigens
Retuximab
Monoclonal antibody … Induce cell-mediated cytotoxicity
Nadolol
Non-selective beta antagonists
Oxaliplatin
Platinum coordinating complex, forms cross-links in guanine
Cisplatin
Platinum coordinating complex, forms cross-links in guanine
Tamsulosin
(Flomax) Alpha-1 antagonists
Terbutaline
Beta-2 agonists
Sarin
Long indirect acting, inhibits AChE
Carvedilol
Non-selective beta antagonists with partial alpha-1 antagonist activity
Salmeterol
Beta-2 agonists
Formoterol
Beta-2 agonists
Cytarabine
Antimetabolite - interferes with cell cycle
Dobutamine
Beta-1 agonist
Metoprolol
Beta-1 selective antagonists
Interferons
Recombinant DNA via bacteria, activation of macrophages and suppression of cell proliferation
Doxazosin
Alpha-1 antagonists
Leuprolide
Steroid Hormones and Antagonists ….. Steroid hormone that is GnRH analog - decrease FSH and LH
Nicotine
Direct acting, agonist for ACh
Terazosin
Alpha-1 antagonists
Phenoxybenzamine
Non-selective alpha antagonists
Cevimeline
Direct acting, agonist for ACh
Propranolol
Non-selective beta antagonists
Dacarbazine
Alkylating Agents
Sildenafil
(Viagra)
Type 5 Phosphodiesterase Inhibitors
Doxorubicin
Antibiotics - induces cytotoxicity
Homatropine
Muscarinic blocker
Carboplatin
Platinum coordinating complex, forms cross-links in guanine
Metaproterenol
Beta-2 agonists
Bleomycin
Antibiotics - scission of DNA
Anastrozole
Steroid Hormones and Antagonists …..
Aromatase inhibitor
Clonidine
Alpha-2 agonists
Neostigmine
Intermediate Indirect acting, inhibits AChE
Paclitaxel
Microtubule Inhibitors- stuck in metaphase
Mechlorethamine
Alkylating Agents
Varenicline (Chantix)
Direct acting, agonist for ACh
Acebutolol
Non-selective beta antagonists with partial agonist effect
Brimonidine
(Alphagan-P)
Alpha-2 agonists
Vinblastine
Microtubule Inhibitors-halts anaphase
Timolol (Timoptic)
Non-selective beta antagonists
Physostigmine
Intermediate Indirect acting, inhibits AChE
Dactinomycin
Antibiotics - interfere with DNA
Prazosin
Alpha-1 antagonists
Albuterol
Beta-2 agonists
Ipratropium (Atrovent)
Muscarinic blocker
Galantamine
Intermediate Indirect acting, inhibits AChE
Malathion
Long indirect acting, inhibits AChE
Phenylephrine
Alpha-1 agonists
Pralidoxime
Reactivates AChE
Flutamide
Steroid Hormones and Antagonists ….. Nonsteroidal antiandroigens
Pindolol
Non-selective beta antagonists with partial agonist effect
Goserelin
Steroid Hormones and Antagonists ….. Steroid hormone that is GnRH analog - decrease FSH and LH
Tadalafil
(Cialis)
Type 5 Phosphodiesterase Inhibitors
Nilutamide
Steroid Hormones and Antagonists ….. Nonsteroidal anti-androigens
Penbutolol
Non-selective beta antagonists with partial agonist effect
Tamoxifen
Steroid Hormones and Antagonists ….. Estrogen antagonist
Yohimbine
Alpha-2 antagonist
Vardenafil
(Levitra)
Type 5 Phosphodiesterase Inhibitors
Tropicamide
Muscarinic blocker
Pyridostigmine
Intermediate Indirect acting, inhibits AChE
Atropine
Muscarinic blocker
Acetylcholine (Miochol)
Direct acting, agonist for ACh
Aminoglutethimide
Steroid Hormones and Antagonists
……Aromatase inhibitor
Echothiophate
Long indirect acting, inhibits AChE
Carmustine
Alkylating Agents
Pilocarpine
Direct acting, agonist for ACh
Scopolamine
Muscarinic blocker
Donepezil
Intermediate Indirect acting, inhibits AChE
Letrozole
Steroid Hormones and Antagonists ….. Aromatase inhibitor
Oxybutynin
Muscarinic blocker
Prednisone
Steroid Hormones and Antagonists ….. Steroid hormone that reduces cell growth and proliferation