Quiz 2

Question 1

Nonselective adrenergic agonist neurotransmitter and function

Answer 1

Epinephrine
Affects all adrenergic receptors
Fight or flight response

Question 2

Adrenergic/cholinergic effects on Beta 1

Answer 2

> HR and BP
Kidneys: > fluid volume

Question 3

What is atropine

Answer 3

Antidote for cholinergic poisoning

Question 4

MOA of atropine

Answer 4

competitively inhibits Ach from binding to muscarinic receptors

Question 5

Indirect-acting cholinergic agonist drug

Answer 5

Acetylcholinesterase (cholinesterase inhibitor)

Question 6

Reasons for taking acetylcholinesterase

Answer 6

Myasthenia Gravis
Alzheimers
(both are due to deficiencies in acetylcholine)

Question 7

Direct acting cholinergic agonist drug and MOA

Answer 7

Bethanechol-stimulates cholinergic receptors on the bladder = promote urination

Question 8

Myasthenia Gravis symptoms

Answer 8

Weakness
Ptosis (drooping of one or both eyelids)
Dipolopia (blurred/double vision)
Unstable/waddling gait
Change in facial expression
Difficulty in chewing, swallowing, breathing

Question 9

Signs of cholinergic poisoning

Answer 9

Salivation
lacrimation
urinary incontinence
Diarrhea
Gastrointestinal cramp
Emesis

Question 10

Drugs for parkinsons: dopamine agonists

Answer 10

Carbidopa-levodopa
Monoamine oxidase B inhibitors (inhibits enzyme destroying dopamine)
Catechol-O-Methlytransferase inhibitors (inhibits inactivating dopamine enzyme)

Question 11

Side effects of dopamine agonists

Answer 11

Dizziness, headache, nausea
Orthostatic hypotension
Suicidal ideation

Question 12

Drugs for parkinson: anticholinergics

Answer 12

Benztropine (congentin)
(adrenergic agonist)

Question 13

Monoamine Oxidase B inhibitors interaction

Answer 13

Foods high in tyramine can cause hypertensive crisis

Question 14

Opioid agonist MOA

Answer 14

CNS depressant, slows all nerves down
Suppresses pain impulses, RR, and coughing
Affects perception and tolerance of moderate to severe pain

Question 15

Opioid Antagonist
MOA

Answer 15

Reverses opioid toxicity
Competes with opioids for receptor sites in the brain and prevents binding with receptors or displaces opioids already occupying receptor sites

Question 16

Opioid agonist/Antagonist MOA

Answer 16

Butorphanol-similar to morphine

Question 17

Adverse effects of morphine

Answer 17

Decreased RR
Decreased BP
Lethargic
Confusion
Constipation
Nausea
Itching-common side effect
Muscles and chest are not ventilation= death

Question 18

Benzodiazepines
Prototype
Use
MOA

Answer 18

Diazepam (Valium)
For stopping status epilepticus
> activity of GABA

Question 19

Barbiturates
Prototype
MOA

Answer 19

Phenobarbital
Depresses cerebral cortex and cerebellum

Question 20

Drugs for preventing seizure

Answer 20

Phenytoin (dilantin)
Gabapentin
Carbamazepine
Valproic acid
Levetiracetam

Question 21

Adverse effects of phenytoin

Answer 21

Gingial hyperplasia/orange urine

Question 22

Adverse effects of all muscle relaxants

Answer 22

Weakness, drowsiness, dizzy, lethargic

Question 23

Centrally acting muscle relaxants

Answer 23

Cyclobenzaprine
Tizanidine

Question 24

Direct acting muscle relaxants

Answer 24

Dantrolene

Question 25

Cause of epilepsy

Answer 25

Secondary to brain trauma, infection, stroke
Isolated seizures due to fever, electrolyte imbalance, alcohol, or drugs
Unknown

Question 26

Adrenergic/cholinergic effects on Alpha 1

Answer 26

Vasoconstriction of blood vessels
Dilation of iris
Bladder retention

Question 27

Adrenergic/cholinergic effects on Alpha 2

Answer 27

Decrease peristalsis and acid, vasodilation of blood vessels

Question 28

Adrenergic/cholinergic effects on Beta 2

Answer 28

> blood glucose
< peristalsis and acid
Bronchodilation = > RR

Question 29

S/S of parkinson

Answer 29

Bradykinesia
Involuntary tremors
Shuffling walk
Pill-rolling motion

Question 30

MOA of anticholinergics

Answer 30

Competitively block Ach receptors
Weaken cholinergic response