Quiz 1 - Moore - Pharyngeal Arches Flashcards
What does branchial mean?
Gills
What would have a greater impact on the organism, a disruption during the formation of the pharyngeal system or a disruption during development of pharyngeal derivatives?
Pharyngeal system
*This is earlier on in the cycle, and can impact more things down the road
DISRUPTIONS TO EITHER PHASE CAN RESULT IN A BROAD SPECTRUM OF DEFECTS
Name 3 syndromes associated with problems in the 1st arch.
Treacher-Collins
Pierre Robin
DiGeorge Syndrome
What is a cyst?
Sealed cavity filled with air, pus, fluid
What is a sinus?
Cavity w/in a tissue, can open externally
What is a fistula?
Abnormal connection b/t 2 structures
- B/t 2 epithelialization surfaces
- Usually b/t 2 hollow structures
- Blind: Open on one end only
- Complete: Openings inside and outside body
- Incomplete: Tube from skin closed on inside, no internal connection
Define migration.
Cells move, or not, during development
Define proliferation.
Growth in cell number thru cell division
Define genetics.
Mutations change patterns in migration, proliferation, etc.
Where do pharyngeal arches emerge at?
Neural tube closure
*Ectodermal pouches filled with mesenchyme
**1st arch is of primary relevance to the face
Which arch shows 2 prominences clearly, and what are the prominences?
1st arch
*Maxillary and mandibular prominences
Ecto
Meso
Endo
Neural crest
Outside
Middle
Inside
Middle (Either from Ecto or meso)
What are the 4 components of pharyngeal arches?
Aortic arch - artery that arises from the truncus arteriosus of the primordial heart, bridge b/t the truncus arteriosus and dorsal aorta, ARISES FROM MESODERM
Cartilaginous rod - Forms the skeleton of the arch
Muscular component - Differentiates into mm in the head and neck
Nerve - Supplies mucosa and mm derived from the arch
Aortic arches 1 and 2 do what?
Largely disappear, but the remains are maxillary, ext carotid, stapedial
Aortic arches 3,4, and 6 do what?
Remodeled to form portions of some large arteries - common and int carotid (3), aortic, subclavian (4), pulmonary (6)
What arch mesoderm gives rise to facial bones?
Arch 1
What are some structures formed by the cartilaginous components of the arches?
Malleus, incus, stapes, styloid process, hyoid, thyroid cartilage, cricoid cartilage
Endochondral ossification comes from where?
Direct from cartilage