Quiz 1- Lecture 4: PET Flashcards

1
Q

What does PET stand for?

A

Positron emission tomography

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2
Q

What is positron emission tomography (PET) based on?

A

The physical properties of isotopes- radioactive forms of simple atoms (like hydrogen, oxygen, fluorine, etc.) emitting positrons when they decay

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3
Q

The atoms of each chemical element have a defining and…
BUT CRUCIALLY

A

Same number of protons and electrons
NOT NEUTRONS, whose numbers can vary

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4
Q

Isotopes are…

A

Atoms with the same number of protons but different numbers of neutrons

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5
Q

Which is the radioactive isotope?
Protium (1H), Deuterium (2H), Tritium (3H)

A

Tritium (3H)- 2 NEUTRONS

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6
Q

What is a positron?

A

Antiparticle of an electron

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7
Q

A positron has all the properties of an electron except for…

Therefore, a positron can simply be considered…

A

The polarity of the electrical charge, which is POSITIVE

An electron having positive unit electrical charge

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8
Q

What happens whenever an electron and a positron come close?

A

They annihilate each other and produce energy in the form of photons

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9
Q

Basic properties of positrons (3):

A
  • Rest mass= 9.11x10^-31 kg = 0.511 MeV/c^2
  • Electrical charge= +1.602x10^-19 C
  • Internal structure: Believed to have no internal structure
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10
Q

Graph:
Each smaller square represents the nucleus of a known…
Black square represents…
All other squares represent…

A

Stable or radioactive isotope
The stable isotope nuclei
The nuclei of radioactive isotopes

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11
Q

Fluorine F18 (3 characteristics):

A
  • Decays by positron
  • (B+) emission
  • Has a half-life of 109.7 minutes
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12
Q

What is it called when Oxygen-18 turns to Fluorine-18?

A

Nuclear transmutation

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13
Q

Adding a proton means…

A

Going up on diagram

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14
Q

Removing a neutron means…

A

Going left on diagram

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15
Q

Labels on PET diagram:

A
  • Positron-emitting nucleus
  • Positron path
  • Positron-Electron annihilation
    -Distance between positron-emitting nucleus and positron-electron annihilation is ~ 0.5 mm
  • annihilation photons on either side of diagram
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16
Q

During 1925-26, quantum theories were proposed that…
HOWEVER

A

Accurately described the energy levels of electrons in atoms
These equations needed to be adapted to Einstein’s theory of relativity

17
Q

In 1928, Paul Dirac…

A

Formulated a fully relativistic quantum theory

18
Q

What did Paul Dirac’s equation do?

What happened later?

A

The equation gave solutions that he interpreted as being caused by a particle equivalent to the electron but with a positive charge

This particle, the positron, was later confirmed through experiments

19
Q

Who was from Tallahassee, Florida?

A

Paul Dirac
The Nobel Prize in Physics 1933
“For the discovery of new productive forms of atomic theory”

20
Q

In developing the quantum mechanical theory, Dirac predicted that…

A

All matter has a kind of mirror image- antimatter

21
Q

What should a particle and its antiparticle have, if charged?

A

Opposite charges

22
Q

By studying the… in a …, in 1932…

A

Tracks of cosmic ray particles; Cloud chamber; Carl Anderson discovered a positively-charged particle with a mass seemingly equal to that of an electron

23
Q

Who discovered the positron?

Anderson’s particle…

A

Carl Anderson (Nobel Prize in Physics 1936)

Was the first antiparticle proven by experiment and was named a “positron”

24
Q

This wonderful item is a… that was used by… and Seth Neddermeyer between 1935 and 1941 at Caltech

A

Cloud chamber; Carl Anderson

25
Q

The cloud chamber served as the…

A

Prototype for a larger (3 ft diameter) chamber that was carried in a B-29 aircraft from 1948 to 1950 to study cosmic rays at high altitudes

26
Q

This particular chamber is unusual in that…

What is the advantage provided?

A

The piston is glass rather than metal

The advantage provided by the glass piston is that it allowed the chamber to be illuminated from below rather than from the side as in conventional designs