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Protein Synthesis Inhibitors > Quinupristin-Dalfopristin > Flashcards

Quinupristin-Dalfopristin Flashcards

1
Q

What is the MOA of streptogamins?

A

Bind to the 50s ribosomal unit, blocking protein synthesis at two different sites.

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2
Q

What is the SOA of streptogamins?

A

Gram (+) bacteria:
VRE faecium
Staph and Streptococcus including MRSA

Bacteriostatic against enterococcus and bactericidal against staph and strep

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3
Q

What is the main use of Streptogamins?

A

Reserved for severe infections caused by VRE when no other options are available.

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Protein Synthesis Inhibitors (7 decks)

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