Clindamycin Flashcards
1
Q
What bacteria does Clindamycin work against?
A
Gram positive bacteria (Staph- including MRSA and strep)
Anaerobes
2
Q
What bacteria is resistant to Clindamycin?
A
C.diff
3
Q
What is the adverse side effect of Clindamycin?
A
C diff associated diarrhea which can result in pseudomembranous colitis. This occurs when there is an overgrowth of C. diff in the gut after the normal flora is disrupted by clindamycin
4
Q
What are potential drug interactions with Clindamycin?
A
Clindamycin and Erythromycin share the same site on the 50S ribosomal unit. When given together, they can cause antagonistic effects making both drugs less effective. They also share cross-resistance. This means that resistance to one can imply resistance to another.
