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FARMA > Quimioterapéuticos > Flashcards

Quimioterapéuticos Flashcards

1
Q

Causa estomatitis por toxicidad

A

Metrotrexato

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2
Q

Causa fibrosis pulmonar por toxicidad

A

Bleomicina

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3
Q

Causa toxicidad cardiaca

A

Doxorubicina

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4
Q

Causa ototoxicidad y nefrotoxicidad

A

Cisplatino

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5
Q

Causa cistitis hemorrágica

A

ciclofosfamida

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6
Q

Causa neuropatía periférica

A

Vincristina/Vinblastina

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7
Q

Son análogos de las purinas (antimetabolitos)

A

Mercatopurina, fludarabina, Clofarabina

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8
Q

Alteran la producción del ADN disminuyendo la fase S

A

Mercatopurina (análogos de purinas)

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9
Q

Tiene una interacción importante con alopurinol

A

Mercatopurina

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10
Q

Análogo de las purinas utilizado en LLLA

A

Mercatopurina

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11
Q

Inhiben a la folato reductasa disminuyendo la fase S

A

Metotrexato

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12
Q

Se utiliza para coriocarcinoma, leucemia meníngea y osteosarcoma

A

Metotrexato

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13
Q

Puede causar aracnoiditis, convulsiones encefalopatía desmielinizante, hiperuricemia, estomatitis, perforación intestinal. Mielo supresión

A

Metotrexato

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14
Q

Son antagonistas del ácido fólico

A

Metotrexato Pemetrexed

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14
Q

Se tiene que suplementar con acido folico

A

Metotrexato, Pemetrexed

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15
Q

Son análogos de las pirimidinas

A

5-fluorouracilo y Gemcitabina

16
Q

Inhiben a la timidilato sintetasa disminuyendo la fase S

A

5-fluorouracilo

17
Q

Se utiliza en múltiples canceres(colon, mama ovario hígado páncreas estomago glioblastoma

A

5-fluorouracilo

18
Q

Puede causar anorexia, N/V, diarrea, mucositis, mielosupresión, alopecia, cardiotoxicidad

A

5-fluorouracilo

19
Q

En mas de un 40% causa anemia, leucopenia, trombocitopenia, dolor, proteinuria, fiebre
y raramente puede causar fibrosis pulmonar, sx urémico hemolítico fatal y encefalopatía

A

Gemcitabina

20
Q

Disminuye la transformación de ribonucleótidos a desoxirribonucleótidos disminuyendo al fase S

A

Hidroxiurea

21
Q
A

FARMA (8 decks)

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