quick overview Flashcards

1
Q

G1

A

Cell grows and prepares for DNA replication.

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2
Q

S

A

DNA is replicated.

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3
Q

G2

A

The cell prepares for mitosis

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4
Q

M

A

The actual division of the nucleus and cell.

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5
Q

what is a tumor supressor gene?

A

a gene that normally regulates cell growth and division, preventing uncontrolled cell growth and tumor development

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6
Q

what happens if tumor supressor genes are mutated?

A

cells can grow out of control, potentially leading to cancer.

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7
Q

what is a proto oncogene?

A

a normal gene that plays a crucial role in regulating cell growth and division

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8
Q

what is an oncogene?

A

a mutated gene that can cause cancer.

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9
Q

how can a proto oncogene become an oncogene?

A

proto-oncogene transforms into an oncogene through various genetic changes, including mutations

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10
Q

binary fission steps (5)

A
  1. DNA replicates
  2. Cell grows and elongates
  3. DNA segregates
  4. A septum begins to form in the center of the cell
  5. The septum fully divides the cell into two identical daughter cells.
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11
Q

what does the m checkpoint check for?

A

chromosome spindle attachment

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12
Q

what does g1 checkpoint check for?

A

the cell checks if it has adequate size, nutrients, and intact DNA

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13
Q

what does the g2 checkpoint check for?

A
  • cell size
  • dna replication
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14
Q

what happens in g1

A

the cell grows and increases the volume of protein and organelles

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15
Q

what happens in s phase

A

cell replicates its DNA

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16
Q

what happens in g2 phase

A

the cell prepares for the mitotic division

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17
Q

what happens in m phase

A

cell division

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18
Q

what is a caspase

A

a protein that regulates programmed cell death (apoptosis) and inflammation

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19
Q

what is a bleb

A

a balloon-like outgrowth of the plasma membrane

20
Q

what is a apoptotic body

A

remnants of cells having undergone apoptosis

21
Q

what is a phagocyte

A

a scavenging cell that engulfs and absorbs cell
particles and bacteria

22
Q

steps of apoptosis (6)

A
  1. Internal or external signals (like DNA damage or stress) trigger apoptosis.
  2. The cell begins to shrink and its membrane starts to bleb
  3. The chromatin (DNA) inside the nucleus condenses and clumps together.
  4. The DNA is broken into small pieces by enzymes (like caspases).
  5. The cell breaks into small, membrane-bound fragments called apoptotic bodies. These bodies contain pieces of the cell, including the fragmented DNA.
  6. The apoptotic bodies are recognized and engulfed by nearby cells (like immune cells), which clean up the cell remnants without causing inflammation.
23
Q

internal triggers of apoptosis

A

cell damage (radiation, damages DNA)

24
Q

external triggers of apoptosis

A

death receptor pathway

25
what is benign
localised masses
26
what is poetentially malignant
localised masses that will eventually invade other tissues and transform into cancer
27
malignant (cancer)
masses that invade ther tissues.
28
what are mutagens
factors that cause mutations in DNA
29
what are carcinogens?
a mutagen which effects TSG's (tumor supressor genes) or protooncogenes
30
carcinogen chemical factor
cigarette smoke
31
carcinogen physical factors
xrays
32
carcinogen biological factors
HPV or cervical cancer
33
what is a neoplasm
An abnormal mass of tissue
34
what are stem cells
cells with the potential to develop into many different types of cells in the body
35
embryonic stem cells
totipotent or pluripotent. can be obtained from IVF programs and replace indefinately.
36
adult stem cells
multipotent or unipotent. function to repair and regenerate damaged or aged tissues. cannot replace indefinately.
37
what is totipotent stem cells
stem cells that can frm any cell type, including placenta
38
what are pluripotent stem cells
stem cells that can frm most cell types, excluding placenta
39
what are multipotent stem cells
can develop into a limited range of cells
40
what are unipotent stem cells
stem cells that can only differenciate into one specific cell type
41
what happens in prophase
chromatin condense into chromosomes
42
what happens in metaphase
chromosomes line up along the metaphase plate
43
what happens in anaphase
sister chrmatids move to opposite ends of the cell
44
what happens in telophase
chromosomes arrive at the cell poles and a nuclear membrane reforms
45
what happens in cytokinesis
the cytoplasm of a cell divides, resulting in two separate daughter cells