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Anesthesia Drug Test Quick Facts > Quick Facts > Flashcards

Quick Facts Flashcards

1
Q

Drugs not cleared with dialysis

A

Propranolol
Nicardepine
Vancomyacin
Verapamil

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2
Q

Drugs contraindicated in a B12 deficiency

A

Nitroprusside

Nitrous Oxide

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3
Q

Tx of Migrainse HA prophalaxis

A

Propranolol

Timolol

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4
Q

Drugs that cause Shivering

A

Thiopental

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5
Q

CYP Inhibitors

A

Cimetidine prolongs diazepam

Erythromycin prolongs diazepam

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6
Q

Drugs that potentiate NMBs

A

Beta Blockers
Calcium Channel Blockers (verapamil, nicardapine, diltiazem)
Furosemide

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7
Q

Drugs that inhibit acetylcholinesterase

A

Esmolol

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8
Q

Drugs to treat increased ICP

A

Furosemide: decrease CSF production by block Na transport in glial tissue
Mannitol: osmotic diuretic

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9
Q

Drugs not given to MG

A

Glycopyrolate
Scopolamine
Tetracaine
Chloroprocaine

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10
Q

Drugs contraindicated with phosphodiasterase/PDE-5 Inhibitors

A 
Nitroglycerine
NTG paste
Prazosin (minipress)
Phenozybenzamine
Phentolamine
Clonidine
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11
Q

Drugs that inhibit Phosphodiesterase

A

Amrinone
Milrinone
Aminophilline
*lead to increased intracellular cAMP and/or cGMP and result in positive inotropic effect and vasodilation

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12
Q

drugs that potentiate cardiac glycosides: DIGOXIN

A

Esmolol (enhances digoxin effects)
Calcium Gluconate/Chloride (contraindicated with suspected/known dig toxicity)
Adenosine (prolongs phase 4 cardiac same as digoxin)
Ancef (increase dig and r/f toxicity)
Azythromycin increases dig levels

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13
Q

Drugs that treat SVT

A 
Phynelephrine
Methozamine (alpha agonist similar to phynelephrine)
Edrophonium
Esmolol
Propranolol
Verapamil
Diltiazem
Adenosine
Digoxin (last choice)
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14
Q

Drugs that prolong QT interval

A 
Droperidol (increase QT)
Promethazine (QT changes)
Ondensetron (prolongs QT)
Sevoflurane
Isoflurane
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15
Q

Drugs that can lead to Pulmonary Edema

A 
Naloxone
Phenylephrine
Isopreterenol
Terbutaline
Propranolol (with cocaine toxicity)
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16
Q

Drugs that may lead to myocardial ischemia

A 
Norepinephrine
Isopreterenol
Dobutamine
Ephedrive
All of these have Beta 1 effects that will stress the heart
17
Q

Do not give to patients with IHSS (idiopathic hypertrophic sub aortic stenosis)

A 
Dobutamine 
Digoxin
Nicardipine
Milrinone (caution)
no spinal or epidural blockes
all of these will really drop BP
18
Q

Give these drugs with IHSS

A

Beta Blockers: Counteract sympathetic activation and ecrease obstruction
Calcium Chennel Blockers
Phenylephrine: OK because it is pure alpha adrenergic agonist and doesn’t augment HT but it does increase SVR. Second choice behind pure maintenance of volume status

19
Q

Do NOT give to 2nd and 3rd degree heart blocks

A 
Atropine (with Mobitz II)
Adenosine
Esmolol
Labetelol
Propranol
Digoxin
most B-blockers
Verapamil
Nicardipine
20
Q

Tx of Prophylactic endocarditis

Moderate risk

A 
Ampicilline IV 2 g 30 min before procedure 
(Allergic to PNC- give 
1- Clindomycin 600 mg or
2- Cefazoline 1 g
or 3- Vancomycine 1 g
21
Q

Tx of Prophylactic endocarditis

High risk

A

Ampicillin IV 2 g 30 minutes and Getamycine 1.5 mg/kg
Allergic to PNC?
give 1. 1 g Vancomycine and Gent. 1.5 mg/kg

22
Q

Nipride and Cyaide toxicity

A

cyanide levels > 2 mcg/dl

thiocyanate level 35-100 mcg/ml

23
Q

s/s of central anticholinergic syndrome

A 
unconsciousness
hallucination
agitation
delirium
dry mouth
tackycardia
atropine flushing
atropine fever
impaired vision
24
Q

what causes central anticholinergic syndrome?

A

increased ACh availability at muscarinic receptors

25
Q

treatment of central anticholinergic syndrome

A

physostrigmine (tertiary amine - XBBB) 0.01-0.03 mg/kg and again in 15-30 minutes

26
Q

Metabolite of esmolol

A

methanol

27
Q

metabolite of aminophysline

A

theophyline

28
Q

metabolite of nitroprusside

A

thycocyonate (HL 2-7 days)

29
Q

metabolite of nitroglycerine

A

nitric oxide (produces vasodilation)

30
Q

metabolite of morphine

A

morphine-6-glucuronide (mu receptors: analgesia and respiratory depression) ESRD metabolite can accumulate and cause RD)

31
Q

metabolite of meperidine

A

normeperidine (CNS stimulant)

32
Q

metabolite of fentanyl

A

norfentanyl (similar to normeperidine) problem is with rental excretion

33
Q

metabolite of vecuronium

A

3-desacytl-vecuronium

34
Q

metabolite of atricurium/cisatricurium

A

laundanozine

35
Q

metabolite of diazepam

A

dexmethyl-diazepam and oxazapam prolong benzo effect 50-100 hours

36
Q

metabolite of ketamine

A

norketamine (1/3 to 1/5 effect of parent drug)

37
Q

drugs that can cause methmeglobinemia

A

nitroglycerine
nitroprusside
prilocaine
benzicaine

38
Q

induction agents good for asthma

A

propofol
etomidate
ketamine

39
Q

do not give to patients with porphyria

A

EMT =
Etomidate
methohexitol
thiopental

Anesthesia Drug Test Quick Facts (19 decks)

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