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Anesthesia Drug Test Quick Facts > Pharmacy Exam Possible Questions > Flashcards

Pharmacy Exam Possible Questions Flashcards

1
Q

how would you treat chest wall rigidity caused by a large dose of opioid that was rapidly administered?

A

give a NMB or an opioid antagonist

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2
Q

what to give for sphincter of oddi spasm?

A
  1. naloxone relieves pain caused by opioid induced biliary spasm but not MI
  2. Glucagon 1-2 mg IM or IV reduces opioid induced biliary spasm, does NOT antagonize the opioid effect
  3. NTG will relieve pain due to biliary spasm or MI
  4. Equal analgesic doses of fentanyl, MS, Demerol increase common bile duct pressure 99, 53, 61 % above pre drug levels respectively
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3
Q

drugs ok to use in open angle glaucoma

A

phenylephrine

epinephrine

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4
Q

what to give for asthma acute

A

Oxygen SaO2 + 95%
inhaled beta agonist albuterol 2-3 puffs q 15-0 min up to 3-4 doses
IV steriods: cortisol 2 mg/kg GTT 0.5 mg/kg/hr or methylprednisolone 60-125 IV q 6 hr
anticholinergics block muscarinic receptors in airway smooth muscle
ipatropium (atrovent) MDI (atropine derivative)
ephedrine/bronchospasm beta 2 effects 20 mg IV
epinephrine 1:1000 bronchospasm 0.1-0.5
(ketamine, sevo, propofol, lidocaine)

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5
Q

what to give for pheo in correct order

A
  1. Alpha adrenergic antagonist- phenoxybenzamine 10-20 mg PO BID non competitive agonist with irreversible alkylation of alpha receptors
  2. phentolamine: acute HTN emergencies that occur with pheochromocytoma manipulation 30-70 mcg/kg (5-20 mg) produces transient decrease in BP may need a continuous infusion
  3. Propranolol: beta blocker too in light of persistent tachycardia or cardiac dysrythmias in the presence of alpha blockade 40 mg PO BID
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6
Q

what not to give in Parkinson’s

A

Droperidol
Reglan
Promethazine
(these are all dopamine antagonists)

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7
Q

Histamine Release

A

SAM
Succynocholine
Atricurium
Mevicurium

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8
Q

Anticholinergic that causes sedtaion

A

Scopalamine

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9
Q

Non sedating anticholinergic

A

glycopyrolate

does not cross BBB

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10
Q

Anticholinergic that causes tackycardia

A

Atropine

scopolamine and glycopyrolate have minimal cardiac effect

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11
Q

What to give in a BB overdose?

A 
Atropine
Isoproterenol
Dobutamine
Glucagon
Calcium Chloride
Epinephrine
Pace Transvenous
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12
Q

dose and ME in BB overdose: atropine

A

7 mcg/kg

vagolytic ie increases HR

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13
Q

dose and ME in BB overdose: isoproterenol

A

2-25 mcg/min IV

pure beta agonist + inotrope/chronotrope

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14
Q

dose and ME in BB overdose: Dobutamine

A

If OD was by selective B1 BB

pure beta agonist increase HR

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15
Q

dose and ME in BB overdose: Glucagon

A

1-10 mg IV followed by 5 mg/hr IV

(increases cAMP in cardiac cells, high doses = inotrope/chronotrope

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16
Q

dose and ME in BB overdose: calcium chloride

A

250-1000 mg IV (5-10 mg/kg)

17
Q

dose and ME in BB overdose: Epi

A

2-10 mcg/min

Beta non selective agonist

18
Q

If you do not have Neo/Glyco and about to extubate what could you use instead?

A

0/5 mg/kg Edrophonium and 7 mcg/kg Atropine

19
Q

what s/e will you see if using Edrophonium/Atropine for reversal?

A

Delayed tackycardia

20
Q

what are the clinical signs of methemoglobinemia?

A

Central Cyanosis
persistent Sa02 in the 80s
hypotension

21
Q

what is the treatment for methemoglobinemia?

A

Methylene Blue: 1-2 mg/kg over 5 min

22
Q

what is the max dose of methylene blue?

A

7-8 mg/kg

23
Q

What drugs can cause methemoglobinemia?

A 
Benzocaine
prilocaine
Nitrates/nitrites/napthalene
Sulfonamides
Dapsone
Chlorates
Aniline
Aminophenones
Nitrobenzene
Phenazopyridine
24
Q

What is the pH of thiopental?

A

pH >10 in solution to preserve it.

alkaline barbituate

25
Q

What do you mix thiopental with and how much?

A

normal saline or sterile H20

20mg/ml stable for 24 hours

26
Q

what can you not mix with thiopental?

A

basic drugs: it NMB- precipitate in tubing

27
Q

what is the pH of barbiturates?

A

ACiDIC

28
Q

Do acids or bases bind to albumin?

A

Acids bind to albumin (acid)

29
Q

Do acids or bases bind to alpha- proteins?

A

Bases bind to alpha proteins (base)

30
Q

what drugs keeps the PDA open?

A

endomethicin

31
Q

what is the shortest acting local anesthetic?

A

chloroprocaine

32
Q

What do you use 0.25% lidocaine for?

A

lower extremity (100-120 cc) Baer Block

33
Q

What do you use 1-2% lidocaine for?

A

Antiarrythmic

Brachial plexus block (30-50cc)

34
Q

what do you use 0.5% lidocaine for?

A

Upper Extremity block (40-50cc) Baer Block

35
Q

what do you use 4 % lidocaine for

A

Transtracheal

36
Q

how much epinephrine is in a concentration of 1:200?

A

5 mcg/cc

37
Q

how much epinephrine is in a concentration of 1:200,000

A

5000 mcg/cc

Anesthesia Drug Test Quick Facts (19 decks)

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