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Path 1 Block 2 > Quan Prim Hemo > Flashcards

Quan Prim Hemo Flashcards

1
Q

Aplastic Anemia

A

Pancytopenia, no myeloid stem cells.

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2
Q

Microangiopathic Hemolytic Anemia

A

Path formation of platelet microthrombi, schistocytes. Seen in TTP and HUS. Skin and mucosa bleeds, fever, renal insuff (HUS) and CNS abnorm (TTP)

Lab = inc bleed time, norm PT/PTT, schistocytes

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3
Q

TTP

A

Decreased ADAMSTS13, skins bleeds, vWF multimer has faulty degradation leading to abnorm platelet adhesion. Usually due to acquired autoAb.

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4
Q

HUS

A

ecoli O157H7

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5
Q

ITP

A

AID = IgG against Gp2b/3a. Spleen prod Abs and eats them.

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6
Q

HIT

A

IgG mediated adverse rxn to Hep. Tx with thrombin inhib (agatroban, lepirudin, bivalirudin)

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7
Q

Drug inhb ADP

A

Ticolpidine/Clopidogrel

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8
Q

Drub monoclonal Ab against GP2b/3a R

A

Abcaximub

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Path 1 Block 2 (5 decks)

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