Qs bank for 1st midterm (P.2) Flashcards

1
Q

Identify compound A in the reaction catalyzed by glutamate dehydrogenase:

Select one:
a. isocitrate
b. ascorbate
c. alpha-Ketoglutarate
d. oxaloacetate
e. malate

A

alpha-Ketoglutarate

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2
Q

Identify compound A in the reaction catalyzed by glutamine synthetase:

Select one:
a. malate
b. L-glutamate
c. alpha-Ketoglutarate
d. oxaloacetate
e. aspartate

A

L-glutamate

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3
Q

Identify compound A in the following reaction catalyzed by glutamine synthetase:

Select one:
a. L-asparagine
b. alpha-Ketoglutarate
c. glutathione
d. L-glutamine
e. L-aspartate

A

L-glutamine

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4
Q

Identify cofactor A utilized in the reaction catalyzed by glutamine synthetase:

Select one:
a. Mg-GTP
b. Mg-GDP
c. Mg-ATP
d. Mg-ADP
e. Mg-UTP

A

Mg-ATP

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5
Q

Identify the cofactor utilized and formed in the reaction catalyzed by glutamine synthetase:

Select one:
a. A is Mg-GTP, B is Mg-ATP
b. A is Mg-ATP, B is Mg- ADP+Pi
c. A is Mg-ADP+Pi, B is Mg- ATP
d. A is Mg-GDP+Pi, B is Mg- GTP
e. A is Mg-GTP, B is Mg- GDP+Pi

A

A is Mg-ATP, B is Mg-ADP+Pi

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6
Q

The synthesis of glutamine catalyzed by glutamine synthetase involves the formation of the following intermedier. Name the intermedier

Select one:
a. aspartyl-phosphate
b. alpha-Ketoglutarate
c. 3-phospho-glycerate
d. 2-phospho-glycerate
e. gamma-glutamyl-phosphate

A

gamma-glutamyl-phosphate

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7
Q

Identify compound A in the reaction catalyzed by alanine aminotransferase:

Select one:
a. Lactate
b. Malate
c. Fumarate
d. Pyruvate
e. Succinate

A

Pyruvate

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8
Q

Identify compound A in the following reaction:

Select one:
a. Glycine
b. Ornithine
c. Alanine
d. Glutamine
e. Lactate

A

c. Alanine

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9
Q

Name the enzyme catalysing the following reaction:

Select one:
a. Aspartate dehydrogenase
b. Glutamate dehydrogenase
c. Pyruvate carboxylase
d. Alanine aminotransferase
e. Pyruvate dehydrogenase

A

d. Alanine aminotransferase

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10
Q

Transamination of pyruvate forms the following compound:

Select one:
a. Lactate
b. Aspartate
c. Alanine
d. Malate
e. Glutamate

A

c. Alanine

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11
Q

Transaminases require the following coenzyme:

Select one:
a. Coenzyme A
b. Lipoic acid
c. Biotin
d. Pyridoxal phosphate
e. FAD

A

d. Pyridoxal phosphate

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12
Q

Identify compound B in the reaction catalyzed by glutamate dehydrogenase:

Select one:
a. citrate
b. L-glutamate
c. alpha-Ketoglutarate
d. oxaloacetate
e. aspartate

A

b. L-glutamate

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13
Q

Transamination of oxaloacetate forms the following compound:

Select one:
a. Pyruvate
b. Aspartate
c. Glutamate
d. Malate
e. Lactate

A

b. Aspartate

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14
Q

The amino donor in the formation of alanine by transamination of pyruvate is the following amino acid:

Select one:
a. Glutamine
b. Asparagine
c. Serine
d. Ornithine
e. Glutamate

A

e. Glutamate

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15
Q

Identify compound A in the reaction catalyzed by alanine aminotransferase:

Select one:
a. Glutamate or Aspartate
b. Asparagine or Glutamine
c. Aspartate or Asparagine
d. Lactate or Malate
e. Arginine

A

a. Glutamate or Aspartate

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16
Q

Identify compound A in the reaction catalyzed by alanine aminotransferase:

Select one:
a. Lactate
b. Fumarate or Malate
c. alpha-Ketoglutarate or oxaloacetate
d. Glutamine or Asparagine
e. Glutamine or Ornithine

A

c. alpha-Ketoglutarate or oxaloacetate

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17
Q

Name the enzyme catalysing the following reaction:

Select one:
a. Aspartate aminotransferase
b. Glutamate oxaloacetate transaminase
c. Glutamine synthetase
d. Asparagine synthetase
e. Asparaginase

A

d. Asparagine synthetase

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18
Q

Identify compound A in the reaction catalyzed by asparagine synthetase:

Select one:
a. L-Glutamate
b. L-Aspartate
c. alpha-Ketoglutarate
d. L-Alanine
e. Oxaloacetate

A

b. L-Aspartate

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19
Q

Identify compound A in the following reaction:

Select one:
a. Alanine
b. Glutamine
c. Asparagine
d. Arginine
e. Glycine

A

c. Asparagine

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20
Q

Identify the cofactor utilized in the reaction catalyzed by asparagine synthetase

Select one:
a. NADH+H+
b. Mg-ATP
c. Acetyl-CoA
d. FADH2
e. Mg-GTP

A

b. Mg-ATP

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21
Q

The following compound provides nitrogen in the conversion of aspartate to asparagine catalyzed by human asparagine synthetase:

Select one:
a. NH4+
b. Alanine
c. Aspartate
d. Glutamine
e. Glutamate

A

d. Glutamine

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22
Q

Name the enzyme catalysing the following reaction:

Select one:
a. Glutamate dehydrogenase
b. Glutamate decarboxylase
c. Glutamate oxaloacetate transaminase
d. Glutaminase
e. Glutamine synthetase

A

a. Glutamate dehydrogenase

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23
Q

What is the sequence of reactions in serine biosynthetic pathway starting from the glycolytic intermedier 3-phosphoglycerate?

Select one:
a. reduction, dephosphorylation, transamination
b. oxidation, transamination, dephosphorylation
c. oxidation, transamination, phosphorylation
d. reduction, transamination, phosphorylation
e. oxidation, dephosphorylation, transamination

A

b. oxidation, transamination, dephosphorylation

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24
Q

Which of the following glycolytic intermedier is oxidized by a dehydrogenase in serine biosynthetic pathway?

Select one:
a. 2-phosphoglycerate
b. 3-phosphoglycerate
c. 1,3-bisphosphoglycerate
d. phosphoenol-pyruvate
e. glyceraldehyde-3-phosphate

A

b. 3-phosphoglycerate

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25
Identify compound A formed from phosphohydroxy- pyruvate in serine biosynthesis: Select one: a. Phosphoenol-pyruvate b. 2-phosphoglycerate c. 3-phosphoglycerate d. glyceraldehyde-3-phosphate e. Phospho-L-serine
e. Phospho-L-serine
26
The type of the reaction shown below is: Select one: a. Transamination b. Amination c. Deamination d. Amidation e. Deamidation
a. Transamination
27
Hydrolytic removal of the phosphoryl group from phospho-L-serine in serine biosynthesis is catalyzed by the following enzyme: Select one: a. phosphoserine-dehydrogenase b. phosphoserine-hydrolase c. serine-dehydrogenase d. serine-hydrolase e. serine synthetase
b. phosphoserine-hydrolase
28
Identify the type of the reaction catalyzed by mitochondrial glutamate dehydrogenase in the direction of L-glutamate formation: Select one: a. oxidative deamination b. oxidative decarboxylation c. oxidative carboxylation d. reductive amination e. reductive decarboxylation
d. reductive amination
29
Interconversion of serine and glycine is catalyzed by the following enzyme: Select one: a. Glycine-N-methyltransferase b. Serine hydroxymethyltransferase c. Serine dehydrogenase d. Glycine aminotransferase e. Glycine dehydrogenase
b. Serine hydroxymethyltransferase
30
Name the enzyme catalyzing the following reaction: Select one: a. Dimethyl-glycine dehydrogenase b. Serine dehydrogenase c. Serine hydrolase d. Serine hydroxymethyltransferase e. Homocysteine-N- methyltransferase
d. Serine hydroxymethyltransferase
31
Identify the amino acid (AA) interconverted to glycine in the following reaction Select one: a. Serine b. Alanine c. Glutamine d. homocysteine e. Glutamate
a. Serine
32
Identify the type of the reaction catalyzed by mitochondrial glutamate dehydrogenase in the direction of alpha-Ketoglutarate formation: Select one: a. oxidative deamination b. oxidative decarboxylation c. oxidative carboxylation d. reductive amination e. reductive decarboxylation
a. oxidative deamination
33
Name the amino acid (AA) interconverted to glycine in the following reaction: Select one: a. Homocysteine b. Serine c. Alanine d. Glutamine e. Aspartate
b. Serine
34
Serine is interconverted to the following amino acid by serine- hydroxymethyltransferase: Select one: a. Alanine b. Cysteine c. Glutamine d. Aspartate e. Glycine
e. Glycine
35
Serine is interconverted to the following amino acid by serine- hydroxymethyltransferase: Select one: a. Alanine b. Cysteine c. Glutamine d. Aspartate e. Glycine
e. Glycine
36
Serine is interconverted to another amino acid (AA) in the reaction shown below. Name the amino acid: Select one: a. Alanine b. Glycine c. Glutamine d. Aspartate e. Cysteine
b. Glycine
37
In the reaction catalyzed by serine-hydroxymethyltransferase enzyme the following cofactor is utilized: Select one: a. Biotin b. NADH+H+ c. Dihydrobiopterin d. Tetrahydrofolate e. Coenzyme A
d. Tetrahydrofolate
38
In the conversion of serine to glycine catalyzed by serine- hydroxymethyltransferase the following cofactor is formed: Select one: a. NAD+ b. FAD c. Methylenetetrahydrofolate d. FADH2 e. Coenzyme A
c. Methylenetetrahydrofolate
39
Identify the cofactor utilized (A) and formed (B) in the reaction catalyzed by serine-hydroxymethyltransferase: Select one: a. A is Methylene- tetrahydrofolate, B is Tetrahydrofolate b. A is Dihydrofolate, B is Tetrahydrofolate c. A is Methylene- tetrahydrofolate, B is Methenyl-tetrahydrofolate d. A is Tetrahydrofolate, B is Methylene-tetrahydrofolate e. A is Formyl-tetrahydrofolate, B is Methenyl-tetrahydrofolate
A is Tetrahydrofolate, B is Methylene-tetrahydrofolate
40
Which amino acid is condensed with serine in the biosynthesis of cysteine? Select one: a. Selenocysteine b. Methionine c. Phospho-serine d. Glycine e. Homocysteine
e. Homocysteine
41
Identify the cofactor utilized and formed in the reaction catalyzed by glutamate dehydrogenase: Select one: a. A is FADH2, B is FAD b. A is FAD, B is FADH2 c. A is NAD(P)H+H+, B is NAD(P)+ d. A is NAD(P)+, B is NAD(P)H+H+ e. A is NADH+H+, B is NADPH+H+
A is NAD(P)H+H+, B is NAD(P)+
42
Serine and compound A are converted to L-homoserine and cysteine. Identify compound A: Select one: a. Homocysteine b. Selenocysteine c. Ascorbate d. Methionine e. Glycine
a. Homocysteine
43
The following enzyme converts phenylalanine to tyrosine: Select one: a. Phenylalanine-hydroxymethyl-transferase b. Phenylalanine-hydroxylase c. Phenylalanine-dehydrogenase d. Phenylalanine-oxidase e. Phenylalanine-decarboxylase
b. Phenylalanine-hydroxylase
44
Identify amino acid (AA) in the reaction shown below: Select one: a. Histidine b. Tryptophane c. Phenylalanine d. Glutamine e. Lysisne
Phenylalanine
45
Phenylalanine-hydroxylase converts phenylalanine to the following compound: Select one: a. Homoserine b. Tyrosine c. Tryptophan d. Alanine e. S-adenosyl-methionine
b. Tyrosine
46
Identify cofactor A utilized in the reaction catalyzed by phenylalanine- hydroxylase: Select one: a. Biotin b. FADH2 c. Tetrahydrobiopterine d. Dihydrofolate e. Tetrahydrofolate
Tetrahydrobiopterine
47
Identify cofactor A formed in the reaction catalyzed by phenylalanine- hydroxylase: Select one: a. Tetrahydrobiopterine b. Tetrahydrofolate c. Dihydrofolate d. Dihydrobiopterine e. Folate
Dihydrobiopterine
48
Phenylalanine-hydroxylase enzyme is a ____________________: Select one: a. oxygenase b. estherase c. dehydrogenase d. isomerase e. mixed function oxidase
e. mixed function oxidase
49
The reaction catalyzed by glutamate dehydrogenase favors glutamate synthesis, which lowers the concentration of cytotoxic compound A. Please name compound A: Select one: a. NO b. H2O2 c. O2- d. ONOO- e. NH4+
NH4+
50
Catalysis by phenylalanine-hydroxylase incorporates one atom of compound A into phenylalanine: Select one: a. H2O2 b. COO- c. O2 d. OH- e. CO2
O2
51
Hydroxylation of peptidyl prolyl and peptidyl lysyl residues of proteins catalyzed by the following enzymes: Select one: a. Phenylalanine-hydroxylase b. Prolyl oxygenase and Lysyl oxygenase c. Prolyl hydroxylase and Lysyl hydroxylase d. Prolyl transferase and Lysyl transferase e. Proline hydrolase and Lysine hydrolase
c. Prolyl hydroxylase and Lysyl hydroxylase
52
Prolyl and lysyl hydroxylase enzymes are __________________. Select one: a. hydrolyses b. estherases c. mixed function oxidases d. isomerases e. oxygenases
c. mixed function oxidases
53
Identify compound A decarboxylated in the reaction catalyzed by prolyl hydroxylase: Select one: a. Oxaloacetate b. Citrate c. Glutamate d. alpha-Ketoglutarate e. Aspartate
alpha-Ketoglutarate
54
Catalysis by prolyl-hydroxylase incorporates one atom of compound A into proline and succinate: Select one: a. H2O2 b. O2 c. NO2 d. CO2 e. COO-
O2
55
Identify cofactor A required in the reaction catalyzed by prolyl hydroxylase: Select one: a. Cu2+ b. Zn2+ c. Fe2+ d. Ca2+ e. Mn2+
Fe2+
56
Identify cofactor A required in the reaction catalyzed by prolyl hydroxylase: Select one: a. NAD+ b. FADH2 c. GTP d. Ascorbate e. Fumarate
Ascorbate
57
Deficiency of the following vitamin required for prolyl and lysyl hydroxylases results in scurvy: Select one: a. Vitamin C b. Vitamin A c. Vitamin E d. Vitamin B6 e. Vitamin B12
a. Vitamin C
58
Glutamate dehydrogenase enzyme of eukaryotes is present in the following cell organelle: Select one: a. endoplasmic reticulum b. peroxisome c. mitochondria d. lysosome e. Golgi apparatus
c. mitochondria
59
Name the enzyme catalyzing the following reaction: Select one: a. Glutamate dehydrogenase b. Glutamate decarboxylase c. Glutamate oxaloacetate transaminase d. Glutamine decarboxylase e. Glutamine synthetase
Glutamine synthetase
60
What is the type of the reaction indicated by A?
A: Transamination
61
What is the type of the reaction indicated by B?
B: Oxidative deamination
62
Identify compound A in the following pathway! Select one: a. glutamate b. glutamine c. α-ketoglutarate d. aspartate e. alanine
α-ketoglutarate
63
Identify cofactor B in the following reaction! Select one: a. NAD(P)H + H+ b. FAD c. NAD(P)+ d. ADP e. ATP
NAD(P)H + H+
64
Identify substrates A and B in the following reaction! Select one: a. A: glutamine, B: glutamate b. A: glutamate, B: α- ketoglutarate c. A: α-ketoglutarate, B: glutamate d. A: glutamate, B: glutamine e. A: α-ketoglutarate, B: glutamine
A: glutamate, B: α- ketoglutarate
65
Which enzyme catalyzes the reaction below? Select one: a. glutaminase b. asparaginase c. α-ketoglutarate dehydrogenase d. glutamine synthase e. glutamate dehydrogenase
d. glutamine synthase
66
Identify substrate A and product B in the following reaction! Select one: a. A: glutamate, B: glutamine b. A: α-ketoglutarate, B: glutamate c. A: aspartate, B: asparagine d. A: oxaloacetate, B: aspartate e. A: α-ketoglutarate, B: glutamine
A: glutamate, B: glutamine
67
Identify compound A in the following reaction! Select one: a. alanine b. aspartate c. pyruvate d. asparagine e. NH4+
NH4+
68
Identify cofactor A in the following reaction! Select one: a. ATP b. NADH + H+ c. NADPH + H+ d. NAD+ e. tetrahydrobiopterin
a. ATP
69
Which enzyme catalyzes the reaction shown below?
glutaminase
70
Identify compounds A and B in the following reaction!
A: H2O, B: NH4+
71
Identify enzyme A in the pathway shown below!
A. carbamoyl phosphate synthase I B. ornithine carbamoyl transferase C. argininosuccinate synthase D. argininosuccinate lyase E. arginase
72
Identify enzyme B in the pathway shown below!
B. ornithine carbamoyl transferase
73
Identify enzyme C in the pathway shown below!
C. argininosuccinate synthase
74
Identify enzyme D in the pathway shown below!
D. argininosuccinate lyase
75
Identify enzyme E in the pathway shown below!
E. arginase
76
Identify compound A in the pathway shown below!
A. carbamoyl phosphate
77
Identify compound B in the pathway shown below!
B. ornithine
78
Identify compound C in the pathway shown below!
C. citrulline
79
Identify compound D in the pathway shown below!
D. argininosuccinate
80
Identify compound E in the pathway shown below!
E. arginine
81
Identify compound A in the pathway shown below!
aspartate
82
Identify compound A in the pathway shown below!
Fumarate
83
What is the allosteric activator of enzyme A?
N-acetylglutamate
84
Identify compounds A and B in the pathway shown below!
A: ATP, B: AMP
85
What are the substrates indicated by A and B?
CO2 and NH4+
86
The figure shows the main pathways of amino acid degradation. What are indicated by A, B and C?
A: acetoacetyl-CoA B: acetyl-CoA C: pyruvate
87
The figure shows the main pathways of amino acid degradation. What are indicated by A, B and C?
A: acetoacetyl-CoA B: acetyl-CoA C: pyruvate
88
The figure shows the main pathways of amino acid degradation. What are indicated by D, E and F?
D: Citrate E: α-ketoglutarate F: glutamate
89
The figure shows the main pathways of amino acid degradation. What are indicated by G, H and I?
G: succinyl-CoA H: fumarate I: oxaloacetate
90
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by A?
A: glutamine, arginine, proline
91
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by A?
A: glutamine, arginine, proline
92
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by A?
A: glutamine, arginine, proline
93
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by B?
B: methionine, isoleucine, valine
94
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by D?
D: asparagine, aspartate
95
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by G?
G: alanine, cysteine, serine
96
The figure shows the main pathways of amino acid degradation. Which amino acids belong to the group indicated by E?
E: leucine, lysine
97
The degradation of the amino acid indicated by A can lead to the formation of succinyl-CoA and acetyl-CoA as well. Which of the following is this amino acid?
isoleucine
98
The degradation of the amino acid indicated by A can lead to the formation of fumarate and acetoacetyl-CoA as well.
phenilalanine
99
Identify enzymes A, B, C and D in the reactions below!
A: asparaginase B: transaminase C: glutaminase D: transaminase
100
Identify compounds A, B and C in the reaction below!
A: asparagine B: aspartate C: oxaloacetate
101
Identify enzyme A in the reaction below!
asparaginase
102
Identify enzyme B in the reaction below!
transaminase
103
Identify compounds A and B in the reaction below!
A: H2O, B: NH4+
104
Which compound can be indicated by D in the following reaction?
alanine
105
Identify compounds A, B and C in the reaction below!
A: glutamine B: glutamate C: α-ketoglutarate
106
Identify enzyme B in the reaction below!
transaminase
107
Which compound can be indicated by D in the following reaction?
alanine
108
Identify compounds A and B in the following reaction!
A: cystine, B: cysteine
109
Which enzyme catalyzes the following reaction?
methionine adenosyltransferase
110
Identify compounds A and B in the following reaction!
A: methionine, B: S-adenosyl-methinonine
111
Identify compounds A and B in the following reaction!
A: ATP, B: Pi + PPi
112
Which enzyme catalyzes the following reaction?
cystathionine β-synthase
113
Identify compound A in the pathway below!
methionine
114
Identify compound B in the pathway below!
S-adenosyl-methionine
115
Identify compound C in the pathway below!
S-adenosyl-homocysteine
116
Identify compound D in the pathway below!
homocysteine
117
Identify compound E in the pathway below!
serine
118
Identify compound F in the pathway below!
cystathionine
119
Identify compound G in the pathway below!
cysteine
120
Identify compound H in the pathway below!
α-ketobutyrate
121
Identify compound I in the pathway below!
propionyl-CoA
122
What is indicated by D and E in the pathway shown below?
D: H2O, E: adenosine
123
The figure below shows the conversion of methionine to propionyl-CoA. Which one of the following compounds is not an intermediate of the pathway?
α-ketoglutarate
124
Identify compound A in the pathway shown below!
Urea