Pyschiatry Flashcards
What is the definition of a delusion, and what are the classifications?
A fixed false belief that is out of context with someone’s cultural, religious and/or ethnic background
Onset classification:
- primary delusions appear suddenly without any mental event leading to them
- secondary delusions appear in response to a morbid experience e.g. Mood change or hallucination etc
Theme classification:
- persecutory/paranoid
- grandiose
- delusions of reference
- delusions of misidentification
- delusions of control
- religious delusions
- delusions of guilt
- nihilistic delusions
- somatic delusions
Describe post traumatic stress disorder (PTSD), its features, and management.
PTSD can develop in people of any age following a traumatic event, for example a major disaster or childhood sexual abused. It encompasses what became known as ‘shell-shock’ following the First World War. One of the DSM-IV diagnostic criteria is that symptoms have been present for more than one month
Features:
- Re-experiencing e.g. flashbacks, nightmares, repetitive and distressing intrusive images.
- Avoidance e.g. avoiding people, situations or circumstances resembling or associated with the event
- Hyperarousal e.g. hypervigilance for threat, exaggerated startle response, sleep problems, irritability, difficulty concentrating
- Emotional numbing e.g. lack of ability to experience feelings, feeling detached.
Management:
- Following a traumatic event single-session interventions (referred to as debriefing) are not recommended
- watchful waiting may be used for mild symptoms lasting less than 4 weeks
- Military personnel have access to treatment provided by the armed forces
- trauma-focused CBT or eye movement desensitisation and reprocessing (EMDR) therapy may be used in more severe cases
- Drug treatments should not be used as a routine first-line, if drug treatment is used the paroxetine or mirtazipine are recommended.
Give examples of disorders of thought content and briefly describe them
- overvalued ideas: content usually understandable, themes tend to be culturally acceptable, tenacity of conviction less than delusions
- delusions: fixed false beliefs that do not fit with persons normal cultural or religious beliefs, may be classified by onset into primary or secondary of classified by theme
Give examples of disturbances of stream of thought
- pressure of thoughts e.g. Ideas arise in an unusual variety and abundance
- poverty of thoughts e.g. Lack of number and variation of thoughts
- thought block e.g. Mind blank
Give examples of disturbances of form of thought
- flight of ideas
- loosening of association e.g. Knights move sudden jump, word salad
- neologism i.e. new word made up by patient that only has meaning to them
- perseveration I.e. Persistent repetition of the same thought
- tangentially e.g. Conversation rapidly drifts from original question and does not come back
- circumstantiality e.g. Conversation drifts but eventually circles back
- blocking e.g. patient answer question appropriately but then do not complete answer, they need the original question to be answered before being able to continue
Describe schizophrenia, it’s symptoms, it’s subtypes, prognostic factors, and management
A psychiatric condition onset usually in 15-45 year olds. Symptoms may be split into positive (hallucinations, delusions, ideas of reference) and negative symptoms:
- under-activity
- few leisure interests
- lack of convention
- social withdrawal
- decreased speech, motivation, emotional responsiveness
First-rank symptoms include:
- auditory hallucinations
- thought withdrawal, insertion, broadcast
- somatic hallucinations
- delusional perceptions
- passivity phenomenon
Subtypes:
- paranoid schizophrenia, usually presenting with prominent delusions usually with hallucinations
-hebephrenic schizophrenia I.e. Prominent disorganised mood, behaviour, speech
-residual schizophrenia I.e. After a period of positive symptoms only
Negative remain
-simple schizophrenia I.e. Only negative symptoms
-catatonic schizophrenia
Poor Prognostic Factors: FHx of schizophrenia, insidious onset, poor pre-morbid personality especially schizoid, low intelligence, absence of precipitating stressor, lack of affective components in the episode, underlying organic disorder.
Management:
- antipsychotics e.g. Typicals (chlorpromazine/ haloperidol) atypicals (risperidone, onlanzapine, clozapine) SEs include weight gain, diabetes, Extrapyramidal, cardiovascular (QT prolonging), hormonal such as prolactinaemia or decreased sexual function.
- psychological e.g. CBT for psychosis, family therapy
- social intervention I.e. Social skills training, housing support etc
Describe first-ranks symptoms of schizophrenia
Symptoms suggestive of schizophrenia if present:
- auditory hallucinations e.g. Hearing thoughts spoken aloud, hearing someone talking about him/her, running commentary
- thought withdrawal, insertion, broadcast
- somatic hallucinations
- delusional perceptions
- passivity phenomena
Describe postnatal depression, it’s symptoms and treatment
Risk of major depression is 3x higher in those with recent pregnancy. Have a low threshold for referring to multidisciplinary teams in mother-and-baby units.
Symptoms: low mood in the post-natal period, loss of appeitite, sleep disturbance.
Treatment:
-risk assess
-CBT
-fluoxetine is as good as CBT in short term, may be started after CBT has failed or there is a history of severe depression:
Describe abbreviated Mental test
10 questions
- Age?
- Time?
- Address to recall at end of the test
- Year?
- Name of this place?
- Identification of two persons?
- DOB
- Yeah of First World War
- Name of monarch
- Count backwards from 20 to 1
Describe the mini mental state exam
Used to indicate presence of cognitive impatient scored out of 30 with 27 as the cut off and 21-26 mild, 10-20 moderate and less than 10 severe.
Tests various categories:
- Orientation in time (5 points)
- Orientation in place (5 points)
- registration I.e. Repeating 3 name prompts (3 points)
- attention and calculation I.e. Serial sevens or world backwards (5 points)
- recall (3 points)
- language I.e name two objects (2 points)
- repetition I.e. Speak back a phrase (1 point)
- complex command I.e 3 point task and intersecting pentagons (6 points)
Describe Beck’s cognitive triad in depression
Consists of negative view of self I.e worthless, dead inside
Negative view of world I.e. Unfair hostile
Negative view of the future I.e. Hopeless, not worth living
Describe Borderline Personality Disorder
There is unstable affect regulation, poor impulse control, and poor interpersonal relationships/self-image. When stressed may hear voices, often self-harm
Associated with ADHD and Learning difficulties. Genetics and adverse child events e.g. Abuse are predispositions.
Describe refeeding syndrome and its signs
A syndrome due to rapid intake of calories typically after a low calorie diet. Monitor Phosphate
Signs: rhabdomyolysis, respiratory or cardiac failure, hypotension, arrhythmias, seizures, coma, sudden death.
Acute gastric dilation can occur if a poorly nourished patient binges. Monitor serum PO4 and stop refeeding if falling, also watch for hyperglycaemia, hypokalemia, and hypermagnesia.
Describe anorexia nervosa, diagnostic criteria, red flags, and treatment
The most fatal of all mental illnesses (~20% if severe). Compulsive need to control eating, low self worth is common and weight loss is an overvalued idea.
Diagnostic Criteria:
- weight less than 85% of predicted (BMI less than 17.5)
- fear of weight gain even when underweight leading to dieting, induced vomiting or excessive exercise
- feeling fat when thin
- amenorrhea (6 consecutive cycles) or decreased libido in men
Red flags:
- BMI less than 13
- weight loss more than 1kg/wk
- body temperature less than 34.5C
- BP less than 80/50 or Pulse less than 40
- SaO2 less than 92%
- weak muscles unable to stand without arms assisting
- ECG showing long QT or flat T waves
Treatment:
- Aim to restore nutritional balance (weight gain of 1.5kg/wk final BMI 20-25).
- Moderate (15-17.5)and mild( 17.5+) self help books and routine referral to community mental health team are sufficient
- Severe anorexia (BMI less than 15 and rapid weight loss and evidence of system failure) requires urgent referral to eating disorder unit if patients lack insight ‘re-feeding’ is considered a treatment under the mental health act. Monitor Phosphate being wary of re-feeding syndrome.
Describe malignant neuroleptic syndrome it’s signs and treatment
It is a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptics or antipsychotic drugs.
Signs:
- hyperthermia
- rigidity
- extrapyramidal signs
- labile BP, tachycardia, sweating, urinary continence
- mutism
- confusion
- coma
- increased WCC
- raised CK
Treatment:
- cooling
- stop antipsychotic
- IV fluids to prevent renal failure
- Dantrolene 1-2.5mg/kg IV (10mg/kg/day) may help with bromocriptine 2.5mg QDS
What is a Community Treatment Order?
For patients under section 3 (Or 3) of the Mental Health Act 2007 that allows enforcement of treatment in the community. Power given to bring patient back to hospital if they do not comply with treatment order.
Describe Section 2 of the Mental Health Act 1983
Describes a compulsory hospitalisation for assessment.
The period of assessment lapses after 28 days.
Patient may appeal, appeal must be sent within 14 days to the Mental Health Tribunal which is composed of a doctor, lay person, and lawyer.
An approved social worker (or the nearest relative) make the application on the recommendation of 2 doctors (not from the same hospital), one of whom ideally both are section 12 approved. The other doctor should ideally know the patient in a professional capacity. If this is not possible, the Code of Practice recommends that the second doctor should be an Approved Doctor
Describe Section 3 of the Mental Health Act 1983
Describes compulsory hospitalisation for treatment lasting upto 6 months.
The exact mental disorder must be stated.
Detention is renewable for a further 6 months (annually thereafter).
2 doctors must sign the appropriate forms and know why treatment in the community is contraindicated. They must have seen the patient within 24h. They must state that treatment is likely to benefit the patient, or prevent deterioration; or that it is necessary for the health or safety of the patient or the protection of others.
Describe Section 5(2) of the Mental Health Act 1983
Describes the compulsory hospitalisation of a patient already in hospital that lasts up to 72hrs, also known as ‘doctor’s holding power’.
The doctor in charge applies, and it is only available to patients on a ward, patients in a+e must be treated under common law.
Describe Section 136 of the Mental Health Act 1983
Valid for upto 72 hours, allows police to arrest a person ‘in a place to which the public have access’ who is believed to be suffering from a mental disorder.
The patient must be conveyed to a ‘place of safety’ (usually a designated a+e or failing that a police station). In hospital there can be full assessment by a doctor and an approved social worker. The patient must be discharged after assessment or detained under section 2 or 3
Describe the Mental Capacity Act 2005
Allows for treatment of patients who are unable to understand, retain, weigh up, or communicate a decision, or are cognitively impaired (MMSE less than 27)
Define Psychosis
A mental health disorder that causes people to perceive or interpret things differently from those around them. This might involve hallucinations and/or delusions.
Describe Bipolar Affective Disorder, its types, signs, treatment
Describes a mood disorder in which there alternating patterns of depression and mania/hypomania (depending on the severity and whether there is psychosis). Increase risk of relapse/episode in pregnancy.
Types:
- Bipolar I, Severe mood episodes from Mania to depression
- Bipolar II, mild mood elevation with hypomania alternating with periods of severe depression.
- Cyclothymia, brief periods of alternating hypomania and mild depression, not as extensive or long lasting as Bipolar.
Signs of Mania:
- Mood: Irritability(80%), Euphoria(71%), Lability(69%)
- Cognition: Grandiosity(78%), Flight of Ideas(71%), Poor concentration(71%), Confusion(25%)
- Behaviour: Rapid Speech(98%), Hyperactivity(87%), Decreased Sleep(81%), Hypersexuality(57%)
- Psychotic symptoms e.g. Delusions, Hallucinations.
Signs of Depression:
- Anhedonia i.e. loss of pleasure/interest
- Poor Appetite
- Early Morning Waking
- Psychomotor Retardation e.g. sluggish thoughts paucity of movements/expressions
- Decreased Sex Drive
- Reduced Concentration
- Ideas of worthlessness and/or guilt
- Thoughts of death, suicide, self harm
Treatment:
- Treat acute moderate/severe mania with olanzapine 10mg PO (SE: Weight Gain, Raised Glucose) or Valproate Semisodium e.g. 250mg/8h PO +/- Anti-psychotic if psychosis
- after successful treatment of the mania or depressive episode should have mood stabiliser for long-term control. If compliance is good and U+E, ECG and T4 normal give Lithium Carbonate 125mg-1/12h PO, Adjust dose to give 0.6-1mmol/L Li on Day 4-7 12 hours post dose. Check lithium levels weekly, until dose constant for 4 weeks then check monthly for 6 months, and then 3 monthly if stable. U+E, TFTs every 6 months as Lithium SE = Hypothyroidism, nephrogenic diabetes insipidus. Stop lithium if blood levels greater than 1.4 mmol/L
- If lithium no tolerated Valproate is used second line as mood stabiliser.
Signs of lithium toxicity: Decreased vision, D+V, Hypokalaemia, ataxia, tremor, dysarthria, coma