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BVM3 Skin > Pyoderma Treatment > Flashcards

Pyoderma Treatment Flashcards

1
Q

What are the 3 types of pyoderma?

A

Surface
Superficial
Deep pyoderma

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2
Q

What is the likely pathogen for surface pyoderma?

A

Unknown - many different causes
Yeasts, Bacteria, etc.

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3
Q

What is the likely pathogen for superficial pyoderma?

A

Over 90% of cases S. pseudintermedius

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4
Q

What is the likely pathogen for deep pyoderma?

A

S. pseudintermedius ~60% cases
Other 40% of cases need lab to diagnose

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5
Q

What is this type of pyoderma and the types of lesions?

A
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6
Q

What is this type of pyoderma and the types of lesions?

A
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7
Q

What is this type of pyoderma and the types of lesions?

A
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8
Q

What is the difference between surface and deep pyoderma? What are the organisms responsible? How does the treatment differ?

A
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9
Q

How does treatment for these 2 causes of pyoderma differ?

A
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10
Q

What currently poses the biggest threat to modern medicine?

A

Drug-resistant bacterial infections

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11
Q

What are the 2 routes of administration for antibacterial therapy for canine pyoderma?

A

Topical application
Systemic route

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12
Q

What are the topical options available for treatment of canine pyoderma? What about systemic?

A

Topical - Shampoos, creams, gels, drops, foam
Systemic - Tablets, Injections

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13
Q

What kinds of infections is topical antibacterial therapy recommended for in canine pyoderma?

A

Recommended for surface and superficial pyoderma as sole therapy
High concentrations achieved at site of infection

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14
Q

What kinds of infections is systemic therapy recommended for in canine pyoderma?

A

For deep pyoderma
In some cases of superficial pyoderma
NEVER for surface infections

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15
Q

Do you need laboratory testing in order to begin topical therapy for treatment of skin infections?

A

No

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16
Q

What are the 2 options for systemic therapy and what are these choices based on?

A
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17
Q

What are some additional considerations you should think about while choosing antibacterial therapy for skin infections?

A

Whether or not the product is licensed
Narrow vs. broad spectrum

18
Q

Why is cytology so ideal for diagnosing surface infections?

A

Identifies relevant pathogen (and therapy)
Monitor progress

19
Q

What are the topical antibacterial products available for use for pyoderma?

A

Fusidic Acid
Chlorhexidine (+/- miconazole)
Polymyxin B (Surolan)
Silver Sulfadiazine
+/- Glucocorticoids - situation dependent

20
Q

What kind of therapy can be used as sole antibacterial in the majority of cases of dogs with surface and superficial pyoderma?

A

Topical antibacterial

21
Q

Is there any clinically relevant resistance described in topical antibacterial use? Is resistance testing needed?

A

No
No resistance testing needed

22
Q

What is the concentration of drug at site of infection with topical antibacterial therapy?

A

High

23
Q

What is CRITICAL in the effectiveness of topical antibacterial therapy?

A

COMPLIANCE

24
Q

What is the typical frequency of shampoo use for topical antibacterial therapy? What about gels or drops?

A

Shampoo - 2-3x per week with 10 min contact
Gel/Drops - 2x daily for 2 weeks

25
Q

Is topical antibacterial therapy for short term or long term use?

A

Suitable for long term use

26
Q

What does topical antibacterial therapy reduce the risk of (think spreading)?

A

Contagion

27
Q

How does the owner benefit from using topical antimicrobial therapies on their pet?

A

Owner can be more in control
Able to use more or less when needed

28
Q

What is the old vs. new system of antimicrobial use for superficial pyoderma?

A
29
Q

How is chlorhexidine used in the majority of dogs with superficial pyoderma?

A

Can work as sole antibacterial therapy

30
Q

What important strain of bacteria is chlorhexidine effective against in canine superficial pyoderma?

A

MRSP

31
Q

What are the first tier drugs if systemic therapy is needed for superficial pyoderma? What must you consider when choosing these drugs?

A

Can be chosen empirically
Need to know knowledge of MRSP prevalence in area

Clindamycin - for dogs with little exposure to abx
Cefalexin
Amoxicillin-Clavulanic acid
TMPS (Potentiated Sulphonamides)

32
Q

What are the second tier drugs if systemic therapy is needed for superficial pyoderma? What must you do before prescribing these drugs?

A

ONLY prescribe after culture and sensitivity testing

Doxycycline/minocycline
Fluoroquinolones
Cefovecin

33
Q

what are the important factors to consider when prescribing systemic therapy for superficial pyoderma? Think - Correct dosing, Duration and follow-up

A
34
Q

What is the brand name of Cefovecin?

A

Convenia

35
Q

What kind of drug is Cefovecin (convenia)?
Spectrum
Duration of action
Method of administration
Activity

A

Broad spectrum
Third generation cephalosporin
Long-acting
Injectable
Activity against gram + and gram - (culture/sensitivity)

36
Q

What is this condition? What should drug choice for this condition always be based on?

A
37
Q

What should you avoid when obtaining a sample for deep pyoderma? What sites should you sample from?

A

Avoid surface bacteria
Swabs from draining tracts/sinuses
Tissue culture from biopsies (into plain pots)
FNA from nodules

38
Q

How long should you treat with systemic antibacterials for superficial pyoderma? What about deep pyoderma?

A
39
Q

What is important to rule out if there is no response to treatment, before considering resistance to an antibiotic?

A

Check compliance

40
Q

What is the difference between resistance and recurrence?

A

Resistance - patient does not respond to antimicrobial therapy (might even worsen)
Recurrence - infection waxes and wanes, keeps coming back due to underlying issue not being resolved

41
Q

What is MRSA/MRSP resistant to? Why are these pathogens important? Are these bacteria more virulent than non-MR variants? Why are they more dangerous?

A
42
Q

Which medications is pet MRSA susceptible to?

A

Tetracyclines
TMPS

BVM3 Skin (5 decks)

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