Pyelonephritis- Sparsh Gupta

Question 1

What is pyelonephritis?

Answer 1

Inflammation of pelvis region of kidney

Question 2

2 variants of pyelonephritis?

Answer 2

1- Acute: Ascending infection and hematogenous infection ( E.coli Mostly, Or Staph saprophyticus)

2- Chronic: Presence of Vesico Ureter Reflux( Bacilli Tubercle)

Question 3

Ascending pathway of Pyelonephritis?

Answer 3

Bacteria due to Instrument(Catheter)—> With the help of peri-urethral skin it colonises Urethra—> into the bladder(Risk of Cystitits)—> Goes into ureter due to disruption of Vesico ureter reflux—> CLIMB UP TO THE RENAL PELVIS

Question 4

Which bacteria mostly causes Acute type of pyelonephritis?

Answer 4

Ascending pathway by E.COLI or sometimes Staph Saprophytic

Descending pathway by Tubercular Bacilli

Question 5

C/F of ascending pyelonephritis?

Answer 5

Fever++ and Dysuria(Burning or painful sensation while urination)

Question 6

Diagnosis of Acute pyelonephritis?

Answer 6

Urine: Microscopic- 1)WBC in urine(Pyuria)
2)WBC cast(when WBC attach themselves to hyaline cast

Culture:

Question 7

What does proteus do?

Answer 7

It causes Xanthogranulomatus pyelonephritis which has Lipid containing macrophages

Question 8

C/F of tubercular Pyelonephritis?

Answer 8

Hematogenously it goes in to kidney—> Lodge—> Lead to caseous necrosis(PUTTY KIDNEY)

With time pelvis degeneration(Calcium deposition also called CEMENTED KIDNEY)

With time complete damage of renal damage( AUTONEPHRECTOMY)

Presence of PSEUDO CALCULI