PVD, Tumors, and Trauma Flashcards

1
Q

What are the main causes of amputation?

A
  • Vascular disease (54%),
  • Trauma (45%)
  • Tumors (less than 2%)
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2
Q

What are common etiologies of vascular disease leading to amputation?

A
  • Diabetes
  • peripheral arterial disease (conditions under the umbrella of PVD)
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3
Q

How is PVD organized based on pathology?

A

PVD is organized into…

  • arterial occlusive
  • inflammatory
  • vasomotor
  • venous disorders
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4
Q

PVD

What are the common arterial and venous symptoms associated with PVD?

A

Arterial:

  • Sharp pain, diminished pulses, cool skin, dry and shiny skin, hairless areas, and trophic changes.

Venous:

  • Aching, heavy legs, swelling, varicose veins, hemosiderin deposits, fibrosis
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5
Q

How can you differentiate arterial vs. venous wounds?

A
  • Arterial wounds are dry, pale, painful, and often distal
  • Venous wounds are often on the lower leg, have drainage, granulation, and hyperpigmentation.
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6
Q

What subjective clues indicate arterial vs. venous disease during evaluation?

A
  • Arterial: Cramping with walking, rest pain relieved by dependency, hairless skin, and cool extremities.
  • Venous: Aching, heavy legs relieved by elevation, and swelling.
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7
Q

What is chronic venous insufficiency (CVI) and what are the symptoms?

A
  • Chronic Venous Insufficiency (CVI) is a condition where damaged valves in veins cause venous hypertension, reverse blood flow, and chronic edema.
  • Symptoms = Dilated veins, leg pain, edema, and stasis dermatitis.
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8
Q

What causes CVI?

A

Venous occlusion, valvular defects, and problems with the muscle pump.

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9
Q

What is peripheral neuropathy?

A

Degeneration of peripheral nerves, affecting sensory, motor, or autonomic functions.

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10
Q

What are the main pediatric bone tumors types?

A
  • Osteosarcoma (56%)
  • Ewing’s sarcoma (34%)
  • Chondrosarcoma (6%)
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11
Q

What are the common symptoms of osteosarcoma and Ewing’s sarcoma?

A

Osteosarcoma:

  • Sharp or dull pain, swelling, redness, limping, and decreased movement of the affected limb.

Ewing’s sarcoma

  • Pain, swelling, fever, weight loss, fatigue, and neurological symptoms if spinal involvement.
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12
Q

Where are osteosarcomas typically located?

A

Lower end of femur, upper end of tibia, upper end of humerus, and upper end of femur.

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13
Q

What is the radiographic appearance of osteosarcoma?

A

Sun-burst appearance, periosteal lifting, permeative bone destruction, and osteolysis.

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14
Q

Where is Ewing’s sarcoma most commonly found?

A
  • femur (45%)
  • pelvis (20%)
  • upper limb (13%)
  • spine/ribs (13%)
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15
Q

What are the radiological features of Ewing’s sarcoma?

A

Permeative bone destruction, laminated periosteal reaction, sclerosis, Codman triangles, and bone expansion.

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16
Q

What are the four key questions in deciding limb salvage vs. amputation?

A
  • Will survival be the same?
  • Will morbidities be the same?
  • Will function improve?
  • Will quality of life improve?
17
Q

How does survival compare between limb salvage and amputation?

A

Survival rates are generally similar between limb salvage and amputation.

18
Q

How do morbidities differ between limb salvage and amputation?

A

Limb salvage tends to have more immediate and late morbidities compared to amputation.

19
Q

Is function improved more by limb salvage or amputation?

A

Limb salvage has a tendency toward improved function, but not overwhelmingly.

20
Q

How does limb salvage impact quality of life (QOL)?

A

Limb salvage has not been proven to offer significantly better psychosocial outcomes than amputation.

21
Q

What are the key symptoms of peripheral neuropathy?

A

Numbness, tingling, weakness, loss of sensation, and autonomic changes.

22
Q

What is the role of the muscle pump in venous return?

A

The muscle pump helps propel blood back to the heart, reducing venous hypertension.

23
Q

What is intermittent claudication?

A

Cramping pain in the legs due to reduced blood flow, typically triggered by exercise.

24
Q

What is rest pain in arterial disease?

A

Pain that occurs at rest, typically relieved by leg dependency, indicating advanced arterial disease.

25
What are trophic skin changes?
Loss of hair, dry skin, and thickened nails due to inadequate arterial blood flow.
26
What skin changes are seen in venous disease?
Hyperpigmentation, hemosiderin deposits, thickened skin, and possible stasis ulcers.
27
How does trauma lead to amputation?
Severe tissue damage, often due to accidents, frostbite, or crush injuries, may require amputation to preserve life.
28
What is the difference between arterial occlusive and venous disease?
Arterial occlusive disease is marked by sharp pain and diminished pulses, while venous disease is associated with aching pain, edema, and present pulses.
29
Why are pulses absent in arterial disease but present in venous disease?
Arterial disease reduces blood flow due to blockages, while venous disease maintains arterial flow but affects venous return.
30
What factors increase the risk of amputation in PVD?
Advanced age, diabetes, smoking, hypertension, and prolonged ischemia.
31
What is stasis dermatitis?
Inflammation of the skin caused by chronic venous insufficiency, leading to itching, redness, and thickened skin.
32
What are the most common sites for venous ulcers?
The medial malleolus and lower leg.
33
What are the most common sites for arterial ulcers?
The toes, feet, and areas distal to the ankle.
34
What is the prognosis for pediatric osteosarcoma with treatment?
Generally good if diagnosed early, with limb salvage being possible in many cases.
35
How does Ewing’s sarcoma differ from osteosarcoma in symptoms?
Ewing's often presents with systemic symptoms like fever and weight loss, while osteosarcoma primarily causes localized pain and swelling.
36
How does limb salvage impact long-term functional outcomes?
It tends to preserve more function compared to amputation, but with potential complications like infection and mechanical failure.
37
What are potential complications of limb salvage surgery?
Infection, prosthetic failure, mechanical issues, and need for further surgeries.
38
Why might limb salvage not improve quality of life?
Due to prolonged rehabilitation, potential complications, and similar survival outcomes compared to amputation.
39
What is the role of radiography in diagnosing bone tumors?
Radiography helps identify tumor type, location, and features like periosteal reactions and bone destruction.