purity Flashcards
1
Q
A
2
Q
What is the parent to Tc-99m?
A
Mo-99
3
Q
What is used to generate Tc-99m?
A
A Mo-99/Tc-99m generator
4
Q
What is the acceptable ratio of mo-99 per mCi of Tc99m?
A
<0.15 uCi Mo-99
5
Q
If the dose of Mo-99 is > 0.15 uCi/mCi Tc99m can it be administered?
A
no
6
Q
Half life of Mo-99
A
67 hr
7
Q
Half life of Tc-99m
A
6 hr
8
Q
What impurities can happen to Tc-99m?
A
Radionuclidic: Mo-99 breakthrough Radiochemical: Hydrolyzed reduced/free pertechnetate Chemical: Aluminum in eluate
9
Q
How do you test Mo-99 breakthrough?
A
Dose calibrator
10
Q
How do you test hydrolyzed reduced/free pertechnetate?
A
thin layer chromatography
11
Q
How do you test aluminum in eluate?
A
Colorimetric test; aurintricarboxylic acid spot test
