Pulmonology Flashcards
What is the trachea made of?
Cartilage
What are the bronchioles made of?
Smooth muscle
Lipoprotein
Prevents alveoli membrane from sticking together
What is the diaphragm made of?
Smooth muscle
What muscle allows ribcages to move during inhalation?
external and internal intercostal muscles
What regulates breathing?
medulla oblongata
What is normal breathing rhythm?
12-20 times per minute
Two chemoreceptors
central chemoreceptor in medulla
peripheral chemoreceptor in aortic and carotid bodies
Central chemoreceptor
- responds only to changes in arterial CO2 levels
- most sensitive receptor and main regulator of breathing
Peripheral chemoreceptor
- monitors low energy levels of oxygen, and high blood acidity (resulting from high CO2 levels)
- only responds when O2 levels drop, but CO2 levels remain normal
What three ways is CO2 waste carried?
- small amount dissolved in water of plasma (9%)
- some attaches to hemoglobin (27%)
- greatest amount reacts with water to produce bicarbonate ions in plasma (64%)
CO2 bicarbonate ion and blood acidity explanation
- the CO2 mixes with water to become H2CO3
- this reaction is sped up with carbonic anhydrase
- H2CO3 is unstable and dissociates quickly
- splits into bicarbonate and hydrogen, which diffuse out of RBC to plasma
- **if you overproduce carbon dioxide, you, through this reaction, overproduce hydrogen, which is acidic and raises your blood pH, which is bad.
- **most CO2 is carried in the bicarbonate ion, obvi.
What buffers the acidity of the blood from CO2?
hemoglobin mixes with the hydrogen, releasing Oxygen, ultimately buffering it.
What happens to the bicarbonate, reduced hemoglobin, and CO2 at the lungs?
the oxygen previously diffused into the plasma dislodges the hydrogen from the hemoglobin, and the hydrogen and bicarbonate become water (vapour) and CO2!
Hypoxia
blood with oxygen levels below 50%
Pleurisy
fluid in lungs, and inflammation of pleural membrane
Cystic fibrosis
genetic. Overproduction of thick mucus in alveoli
Pneumonia
often caused by an infection, the alveoli fill with thick fluid, making gas exchange difficult.
Bronchitis
airways are inflamed due to infection (acute) or due to an irritant (chronic). Coughing brings up mucus.